Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | GCK | P35557 | 3/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KLK7 | P49862 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | TYK2 | P29597 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6801935 | 0.93 | MAPK1 (0.42) | HPGDALDH1A1KDM4EMAPK1KMT2A | |
| SCHEMBL6802820 | 0.86 | KMT2A (0.43) | HPGDALDH1A1MAPK1KMT2AMAPK8 | |
| SCHEMBL6809060 | 0.83 | MAPK14 (0.42) | HPGDALDH1A1KDM4EMAPK1KMT2A | |
| SCHEMBL6801883 | 0.78 | MAPK14 (0.46) | HPGDALDH1A1KDM4EMAPK1KMT2A | |
| SCHEMBL6799622 | 0.78 | JAK2 (0.43) | HPGDALDH1A1KDM4EMAPK1KMT2A | |
| SCHEMBL7847622 | 0.76 | MAPK14 (0.42) | HPGDALDH1A1KDM4EMAPK1KMT2A | |
| SCHEMBL6802805 | 0.75 | RAB9A (0.43) | HPGDMAPK1KMT2AMAPTHTT | |
| Hydrochloric Acid SCHEMBL6803745 | 0.75 | MAPK14 (0.41) | HPGDALDH1A1KDM4EMAPK1KMT2A | |
| SCHEMBL6803041 | 0.70 | RAB9A (0.48) | HPGDMAPK1MAPTHTTSMN1; SMN2 | |
| SCHEMBL6800391 | 0.70 | HPGD (0.43) | HPGDALDH1A1MAPK8MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048880-A | THERAPY FOR CYTOKINE SENSITIVE DISEASES | PFIZER PHARAMACEUTICALS INC. (JP) | 2000-04-11 | — | — | US | disclosed |