Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 7/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FPR1 | P21462 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL785495 | 0.94 | F10 (0.42) | F10TRPV1FPR1FPR2 | |
| SCHEMBL785887 | 0.92 | TRPV1 (0.42) | F10TRPV1 | |
| SCHEMBL784229 | 0.92 | TRPV1 (0.44) | TRPV1MEN1KMT2A | |
| SCHEMBL784882 | 0.92 | ALDH1A1 (0.41) | F10MEN1KMT2AMAPT | |
| SCHEMBL784341 | 0.90 | F10 (0.41) | F10TRPV1 | |
| SCHEMBL784761 | 0.90 | F10 (0.40) | F10TRPV1FPR1FPR2MAPT | |
| SCHEMBL784253 | 0.89 | TRPV1 (0.42) | F10TRPV1MEN1KMT2A | |
| SCHEMBL784198 | 0.88 | F10 (0.41) | F10TRPV1MEN1KMT2AMAPT | |
| SCHEMBL785838 | 0.87 | TRPV1 (0.44) | F10TRPV1MEN1KMT2AFPR1 | |
| SCHEMBL785722 | 0.87 | TRPV1 (0.42) | F10TRPV1MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120071461-A1 | Substituted Benzamide Compounds | GRUENENTHAL GMBH (DE) | 2012-03-22 | — | — | US | claimed |
| US-8680159-B2 | Bradykinin 1 receptor modulating compounds | GRUENENTHAL GMBH (DE) | 2014-03-25 | — | — | US | disclosed |
| US-20120071461-A1 | Substituted Benzamide Compounds | GRUENENTHAL GMBH (DE) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071461-A1 | Substituted Benzamide Compounds | BDKRB1, BDKRB2, HRH2 | F10 524/4885TRPV1 21/4885MEN1 2563/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.