Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | GCK | P35557 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31260118 | 0.81 | SLC6A2 (0.39) | KMT2AALDH1A1MAPTSMN1; SMN2HTT | |
| SCHEMBL13889408 | 0.76 | KMT2A (0.49) | KMT2AMKNK1MKNK2ALDH1A1ATM | |
| SCHEMBL8225216 | 0.71 | LMNA (0.44) | MKNK2ALDH1A1MAPK1SMN1; SMN2HTT | |
| SCHEMBL17424876 | 0.71 | LMNA (0.44) | MKNK2ALDH1A1MAPK1SMN1; SMN2HTT | |
| SCHEMBL8329884 | 0.70 | SLC6A2 (0.43) | MKNK2ALDH1A1MAPK1SMN1; SMN2HTT | |
| SCHEMBL8329882 | 0.70 | SLC6A2 (0.43) | MKNK2ALDH1A1MAPK1SMN1; SMN2HTT | |
| SCHEMBL325007 | 0.69 | SMN1; SMN2 (0.65) | KMT2AMKNK1MKNK2ALDH1A1MAPK1 | |
| SCHEMBL29506761 | 0.69 | SMN1; SMN2 (0.65) | KMT2AMKNK1MKNK2ALDH1A1MAPK1 | |
| SCHEMBL13357525 | 0.69 | CDC7 (0.49) | MKNK2ALDH1A1MAPK1SMN1; SMN2HTT | |
| SCHEMBL9045388 | 0.68 | ALDH1A1 (0.41) | ALDH1A1SMN1; SMN2HTTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150565-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION bioscience AG (DE) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000045635-A1 | THIAZOLE DERIVATIVES AND COMBINATORIAL LIBRARIES THEREOF | LION BIOSCIENCE AG (DE) | 2000-08-10 | — | — | WO | disclosed |