Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 6/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.35 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.35 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CCKBR | P32239 | 1/20 | 0.33 |
| ▸ | MPO | P05164 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.33 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.33 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.33 |
| ▸ | ITGAL | P20701 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8462876 | 0.94 | GHSR (0.39) | GHSROPRM1HTR2AHTR2CADAM17 | |
| SCHEMBL7930529 | 0.78 | GHSR (0.46) | GHSROPRM1ACE | |
| Hydrochloric Acid SCHEMBL7575092 | 0.78 | GHSR (0.42) | GHSROPRM1MEN1KMT2AACE | |
| SCHEMBL7654721 | 0.76 | GHSR (0.49) | GHSROPRM1ACE | |
| SCHEMBL6981470 | 0.72 | GHSR (0.52) | GHSR | |
| SCHEMBL6981466 | 0.72 | GHSR (0.52) | GHSR | |
| SCHEMBL8161727 | 0.71 | GHSR (0.39) | GHSR | |
| Hydrochloric Acid SCHEMBL7571696 | 0.71 | GHSR (0.37) | GHSRMEN1KMT2AACE | |
| SCHEMBL5615895 | 0.71 | GHSR (0.42) | GHSROPRM1MEN1KMT2AACE | |
| SCHEMBL5616078 | 0.71 | GHSR (0.42) | GHSROPRM1MEN1KMT2AACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1070064-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | Merck & Co., Inc. (US) | 2001-01-24 | — | — | EP | disclosed |
| WO-1999051596-A1 | ANTAGONISTS OF GONADOTROPIN RELEASING HORMONE | MERCK & CO., INC. (US) | 1999-10-14 | — | — | WO | disclosed |