Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL896326 | 0.76 | CHRM2 (0.31) | CHRM2CHRM1CHRM3 | |
| SCHEMBL7856061 | 0.70 | DPP4 (0.41) | CHRM2CHRM1CHRM3DPP4 | |
| SCHEMBL895307 | 0.70 | DPP4 (0.41) | CHRM2CHRM1CHRM3DPP4 | |
| SCHEMBL647255 | 0.68 | DPP4 (0.41) | DPP4 | |
| SCHEMBL7859357 | 0.68 | ELANE (0.34) | CHRM2CHRM1CHRM3 | |
| SCHEMBL648669 | 0.68 | DPP4 (0.42) | DPP4 | |
| SCHEMBL7856846 | 0.67 | DPP4 (0.62) | DPP4 | |
| SCHEMBL896165 | 0.67 | DPP4 (0.62) | DPP4 | |
| SCHEMBL7857237 | 0.67 | DPP4 (0.62) | DPP4 | |
| SCHEMBL3742876 | 0.67 | ELOVL6 (0.39) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010146597-A1 | 2-AMINO-2- [8-(DIMETHYL CARBAMOYL)- 8-AZA- BICYCLO [3.2.1] OCT-3-YL]-EXO- ETHANOYL DERIVATIVES AS POTENT DPP-IV INHIBITORS | LUPIN LIMITED (IN) | 2010-12-23 | — | — | WO | disclosed |