Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | CA12 | O43570 | 1/20 | 0.61 |
| ▸ | CA1 | P00915 | 1/20 | 0.61 |
| ▸ | CA2 | P00918 | 1/20 | 0.61 |
| ▸ | CA7 | P43166 | 1/20 | 0.61 |
| ▸ | CA9 | Q16790 | 1/20 | 0.61 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.61 |
| ▸ | HSD11B1 | P28845 | 3/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22305103 | 0.90 | CA12 (0.71) | POLBCA12CA1CA2CA7 | |
| SCHEMBL6985975 | 0.90 | CA12 (0.71) | POLBCA12CA1CA2CA7 | |
| SCHEMBL9364495 | 0.85 | EPHX2 (0.77) | POLBCA12CA1CA2CA7 | |
| SCHEMBL17573009 | 0.83 | HSP90AA1 (0.54) | POLBHSP90AA1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL3047748 | 0.83 | CA12 (0.63) | POLBCA12CA1CA2CA7 | |
| SCHEMBL10194850 | 0.83 | PKM (0.72) | HSP90AA1MEN1KMT2ASLC6A7KDM4E | |
| SCHEMBL643480 | 0.82 | ALDH1A1 (0.69) | POLBCA12CA1CA2CA7 | |
| SCHEMBL31334408 | 0.82 | HPGD (0.76) | POLBCA12CA1CA2CA7 | |
| SCHEMBL28231369 | 0.82 | POLB (0.58) | POLBCA12CA1CA2CA7 | |
| SCHEMBL2646094 | 0.81 | HPGD (0.70) | POLBCA12CA1CA2CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1118612-A1 | Piperazine derivatives possesing nootropic activity | Universita Degli Studi di Firenze (IT) | 2001-07-25 | — | — | EP | claimed |
| EP-1118612-A1 | Piperazine derivatives possesing nootropic activity | Universita Degli Studi di Firenze (IT) | 2001-07-25 | — | — | EP | disclosed |