Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7849725 | 0.98 | LMNA (0.50) | CYP1A2CYP2C9CYP2C19KMT2AMAPT | |
| SCHEMBL3135214 | 0.95 | CYP1A2 (0.55) | CYP1A2CYP2C9CYP2C19KMT2AMAPT | |
| SCHEMBL7850916 | 0.89 | CYP1A2 (0.43) | CYP1A2CYP2C9CYP2C19KMT2AMAPT | |
| SCHEMBL7849178 | 0.81 | ALDH1A1 (0.50) | CYP1A2CYP2C19MAPTL3MBTL1NPSR1 | |
| SCHEMBL10362099 | 0.81 | LMNA (0.50) | CYP1A2CYP2C9CYP2C19KMT2AMAPT | |
| SCHEMBL30096940 | 0.80 | CYP1A2 (0.63) | CYP1A2CYP2C9CYP2C19KMT2AMAPT | |
| SCHEMBL6651604 | 0.80 | CYP1A2 (0.63) | CYP1A2CYP2C9CYP2C19KMT2AMAPT | |
| Bromide SCHEMBL1093529 | 0.80 | MEN1 (0.47) | CYP1A2CYP2C9CYP2C19KMT2AMAPT | |
| Hydrochloric Acid SCHEMBL1093190 | 0.80 | MEN1 (0.47) | CYP1A2CYP2C9CYP2C19KMT2AMAPT | |
| SCHEMBL1964196 | 0.78 | LMNA (0.62) | CYP1A2CYP2C9CYP2C19KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0953564-B1 | Process for preparing 2-cyanobiphenyl compound | SUMIKA FINE CHEMICALS CO LTD (JP) | 2001-06-13 | — | — | EP | disclosed |
| EP-0854135-B1 | Process for preparing 2-cyanobiphenyl compound | SUMIKA FINE CHEMICALS CO LTD (JP) | 2000-02-02 | — | — | EP | disclosed |
| US-5998652-A | Process for preparing 2-cyanobiphenyl compound | SUMIKA FINE CHEMICALS CO., LTD. (JP) | 1999-12-07 | — | — | US | disclosed |
| EP-0953564-A1 | Process for preparing 2-cyanobiphenyl compound | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 1999-11-03 | — | — | EP | disclosed |
| EP-0854135-A2 | Process for preparing 2-cyanobiphenyl compound | SUMIKA FINE CHEMICALS Co., Ltd. (JP) | 1998-07-22 | — | — | EP | disclosed |