Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6077494 | 0.90 | MTNR1A (0.42) | MTNR1AMTNR1BSLC2A1 | |
| SCHEMBL6076454 | 0.77 | MTNR1A (0.49) | MTNR1AMTNR1BSLC2A1 | |
| SCHEMBL5335531 | 0.76 | EGLN1 (0.46) | MTNR1AMTNR1B | |
| SCHEMBL5344998 | 0.75 | MTNR1A (0.50) | MTNR1AMTNR1B | |
| SCHEMBL5343898 | 0.74 | MTNR1A (0.49) | MTNR1AMTNR1B | |
| SCHEMBL5351881 | 0.74 | MTNR1A (0.49) | MTNR1AMTNR1B | |
| SCHEMBL8705200 | 0.74 | MTNR1A (0.58) | MTNR1AMTNR1BSLC2A1 | |
| SCHEMBL8873933 | 0.74 | MTNR1A (0.58) | MTNR1AMTNR1BSLC2A1 | |
| SCHEMBL6077487 | 0.74 | MTNR1A (0.43) | MTNR1AMTNR1BSLC2A1 | |
| SCHEMBL6077489 | 0.71 | NCEH1 (0.45) | MTNR1AMTNR1BSLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1077927-A1 | NOVEL SUBSTITUTED CYCLIC COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058495-A1 | NOVEL SUBSTITUTED CYCLIC COMPOUNDS, PREPARATION METHOD AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | ADIR ET COMPAGNIE (FR) | 1999-11-18 | — | — | WO | disclosed |