Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.58 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.58 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8873933 | 1.00 | MTNR1A (0.58) | MTNR1AMTNR1BSLC2A1 | |
| SCHEMBL8186004 | 0.84 | MTNR1A (0.61) | MTNR1AMTNR1B | |
| SCHEMBL27229065 | 0.83 | MTNR1A (0.53) | MTNR1AMTNR1B | |
| SCHEMBL3915704 | 0.82 | MTNR1A (0.73) | MTNR1AMTNR1B | |
| SCHEMBL5344998 | 0.82 | MTNR1A (0.50) | MTNR1AMTNR1B | |
| SCHEMBL8708804 | 0.81 | MTNR1A (0.61) | MTNR1AMTNR1B | |
| SCHEMBL6076454 | 0.81 | MTNR1A (0.49) | MTNR1AMTNR1BSLC2A1 | |
| SCHEMBL5351881 | 0.81 | MTNR1A (0.49) | MTNR1AMTNR1B | |
| SCHEMBL5343898 | 0.81 | MTNR1A (0.49) | MTNR1AMTNR1B | |
| SCHEMBL6077489 | 0.80 | NCEH1 (0.45) | MTNR1AMTNR1BSLC2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591057-B1 | Arylalkyl(thio)amides with melatonine receptor selectivity and process for their preparation | ADIR (FR) | 1996-07-10 | — | — | EP | claimed |
| US-5464872-A | Sleep disorders | ADIR ET COMPAGNIE (FR) | 1995-11-07 | — | — | US | claimed |
| EP-0591057-A1 | Arylalkyl(thio)amides with melatonine receptor selectivity and process for their preparation | ADIR ET COMPAGNIE (FR) | 1994-04-06 | — | — | EP | claimed |
| US-5708020-A | FOR TREATING SLEEP DISORDERS | ADIR ET COMPAGNIE (FR) | 1998-01-13 | — | — | US | disclosed |
| EP-0591057-B1 | Arylalkyl(thio)amides with melatonine receptor selectivity and process for their preparation | ADIR (FR) | 1996-07-10 | — | — | EP | disclosed |
| US-5464872-A | Sleep disorders | ADIR ET COMPAGNIE (FR) | 1995-11-07 | — | — | US | disclosed |
| EP-0591057-A1 | Arylalkyl(thio)amides with melatonine receptor selectivity and process for their preparation | ADIR ET COMPAGNIE (FR) | 1994-04-06 | — | — | EP | disclosed |