Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 2/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.39 |
| ▸ | TPH1 | P17752 | 2/20 | 0.35 |
| ▸ | TPH2 | Q8IWU9 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MTOR | P42345 | 4/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8182725 | 0.95 | GRIN1 (0.42) | GRIN1GRIN2BTPH1TPH2ALDH1A1 | |
| SCHEMBL7076081 | 0.89 | GRIN1 (0.34) | GRIN1GRIN2BALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7846561 | 0.83 | GRIN1 (0.38) | GRIN1GRIN2BALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL6087285 | 0.83 | GRIN1 (0.39) | GRIN1GRIN2BTPH1TPH2ALDH1A1 | |
| SCHEMBL7846211 | 0.81 | MEN1 (0.36) | GRIN1GRIN2BALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL7067487 | 0.81 | GRIN1 (0.39) | GRIN1GRIN2BTPH1TPH2ALDH1A1 | |
| SCHEMBL8337012 | 0.81 | MAPT (0.35) | GRIN1GRIN2BALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL6088074 | 0.80 | GRIN1 (0.39) | GRIN1GRIN2BTPH1TPH2ALDH1A1 | |
| SCHEMBL7841353 | 0.80 | GRIN1 (0.34) | GRIN1GRIN2BTPH1TPH2ALDH1A1 | |
| SCHEMBL6087020 | 0.78 | GRIN1 (0.43) | GRIN1GRIN2BTPH1TPH2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100786-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000061564-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-10-19 | — | — | WO | disclosed |