Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.30 |
| ▸ | ADCY8 | P40145 | 1/20 | 0.30 |
| ▸ | ADCY1 | Q08828 | 1/20 | 0.30 |
| ▸ | TPMT | P51580 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7847521 | 0.86 | LMNA (0.41) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL9009363 | 0.85 | TPH1 (0.34) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7854604 | 0.84 | MAPT (0.49) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL9009353 | 0.84 | USP2 (0.38) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL8182725 | 0.83 | GRIN1 (0.42) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7847828 | 0.82 | MEN1 (0.33) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL9009425 | 0.82 | MEN1 (0.33) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7844325 | 0.81 | TYMS (0.35) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL7848699 | 0.81 | GRIN1 (0.39) | MEN1KMT2AALDH1A1SMN1; SMN2GRIN1 | |
| SCHEMBL7848458 | 0.81 | MAPT (0.36) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100786-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | Samjin Pharmaceutical Co., Ltd. (KR) | 2001-05-23 | — | — | EP | disclosed |
| WO-2000061564-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-10-19 | — | — | WO | disclosed |
| WO-2000061563-A1 | ANTIVIRAL PYRIMIDINEDIONE DERIVATIVES AND PROCESS FOR THE PREPARATION THEREOF | SAMJIN PHARMACEUTICAL CO., LTD. (KR) | 2000-10-19 | — | — | WO | disclosed |