Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SI | P14410 | 1/20 | 0.40 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29127308 | 0.98 | CYP1A2 (0.52) | ALDH1A1CYP1A2TSHRUSP2LMNA | |
| SCHEMBL31252127 | 0.96 | ALDH1A1 (0.44) | ALDH1A1CYP1A2TSHRUSP2LMNA | |
| SCHEMBL7848700 | 0.92 | GAA (0.46) | ALDH1A1CYP1A2TSHRUSP2LMNA | |
| SCHEMBL4577419 | 0.90 | GAA (0.44) | ALDH1A1CYP1A2TSHRUSP2LMNA | |
| SCHEMBL13945296 | 0.83 | ALDH1A1 (0.43) | ALDH1A1CYP1A2TSHRUSP2LMNA | |
| SCHEMBL10566062 | 0.83 | OPRM1 (0.44) | KMT2A | |
| SCHEMBL6583167 | 0.82 | ALDH1A1 (0.53) | ALDH1A1CYP1A2TSHRUSP2LMNA | |
| SCHEMBL11417985 | 0.81 | GAA (0.40) | ALDH1A1CYP1A2TSHRUSP2LMNA | |
| SCHEMBL4691068 | 0.81 | ALDH1A1 (0.57) | ALDH1A1CYP1A2TSHRUSP2LMNA | |
| SCHEMBL3819838 | 0.81 | ALDH1A1 (0.57) | ALDH1A1CYP1A2TSHRUSP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7537765-B2 | Inhibition of HIV-1 replication by disruption of the processing of the viral capsid-spacer peptide 1 protein | PANACOS PHARMACEUTICALS, INC. (US) | 2009-05-26 | — | — | US | disclosed |
| EP-0767790-B1 | CONDENSED IMIDAZOLE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-12-12 | — | — | EP | disclosed |
| US-5840732-A | ANTIDIABETIC AGENTS, AUTOIMMUNE DISEASES OR IMMUNOSUPPRESSANTS | TAKEDA CHEMICAL INDUSTRIES LTD. (JP) | 1998-11-24 | — | — | US | disclosed |
| EP-0767790-A1 | CONDENSED IMIDAZOLE COMPOUNDS, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1997-04-16 | — | — | EP | disclosed |
| WO-1995035296-A1 | CONDENSED IMIDAZOLE COMPOUNDS, THEIR PRODUCTION AND USE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1995-12-28 | — | — | WO | disclosed |