Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.35 |
| ▸ | CCR4 | P51679 | 2/20 | 0.34 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7854314 | 0.90 | SLC40A1 (0.36) | SLC40A1CCR4PDE4AMEN1KMT2A | |
| SCHEMBL7851095 | 0.80 | TSHR (0.36) | SLC40A1CCR4TSHRLMNA | |
| SCHEMBL7853022 | 0.79 | GAA (0.47) | SLC40A1PDE10AKMT2ATSHRPDE4D | |
| SCHEMBL8890841 | 0.77 | TSHR (0.35) | SLC40A1CCR4TSHRALDH1A1LMNA | |
| SCHEMBL8883100 | 0.77 | TSHR (0.39) | SLC40A1CCR4TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL8883188 | 0.76 | NPSR1 (0.34) | CCR4KMT2ATSHRLMNASMN1; SMN2 | |
| SCHEMBL8881103 | 0.76 | HTT (0.35) | CCR4TSHRALDH1A1 | |
| SCHEMBL7855692 | 0.74 | TSHR (0.32) | CCR4TSHRSMN1; SMN2 | |
| SCHEMBL8881335 | 0.74 | TSHR (0.37) | TSHRALDH1A1LMNA | |
| SCHEMBL7853356 | 0.74 | TSHR (0.38) | MEN1KMT2ATSHRALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0717743-B1 | N-ARYL 1,2,4]TRIAZOLO 1,5-a]PYRIDINE-2-SULFONAMIDE HERBICIDES | DOW AGROSCIENCES LLC (US) | 2001-11-14 | — | — | EP | disclosed |
| EP-0972774-A2 | 2-Benzylthio-8-amino(1,2,4)triazolo(1,5-pyridines | Dow AgroSciences LLC (US) | 2000-01-19 | — | — | EP | disclosed |
| US-5571775-A | EFFECTIVE ON A BROAD SPECTRUM OF VEGETATION AT LOW APPLICATION RATES | DOWELANCO (US) | 1996-11-05 | — | — | US | disclosed |
| WO-1996001826-A1 | N-ARYL[1,2,4]TRIAZOLO[1,5-a]PYRIDINE-2-SULFONAMIDE HERBICIDES | DOWELANCO (US) | 1996-01-25 | — | — | WO | disclosed |