Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.67 |
| ▸ | RAB9A | P51151 | 7/20 | 0.67 |
| ▸ | MEN1 | O00255 | 5/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.65 |
| ▸ | AURKA | O14965 | 1/20 | 0.61 |
| ▸ | PIM1 | P11309 | 1/20 | 0.61 |
| ▸ | CDK2 | P24941 | 1/20 | 0.61 |
| ▸ | GSK3B | P49841 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | CASP3 | P42574 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.51 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.51 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27657075 | 0.83 | KMT2A (0.83) | NPC1KMT2ARAB9AMAPK1MAPT | |
| SCHEMBL15113555 | 0.82 | KMT2A (0.60) | NPC1KMT2AMEN1MAPTSMN1; SMN2 | |
| SCHEMBL16217138 | 0.81 | RAB9A (0.56) | NPC1KMT2ARAB9AMEN1MAPK1 | |
| SCHEMBL8895139 | 0.81 | RAB9A (1.00) | NPC1KMT2ARAB9AMEN1MAPT | |
| SCHEMBL31078859 | 0.76 | KMT2A (1.00) | NPC1KMT2ARAB9AMEN1MAPK1 | |
| SCHEMBL4600722 | 0.76 | AURKA (1.00) | NPC1KMT2ARAB9AMEN1MAPK1 | |
| SCHEMBL27854284 | 0.76 | KMT2A (0.62) | NPC1KMT2ARAB9AMEN1MAPK1 | |
| SCHEMBL6284808 | 0.75 | CDK2 (0.64) | NPC1KMT2ARAB9AMAPK1CDK2 | |
| SCHEMBL5343265 | 0.74 | CDK5 (0.69) | NPC1KMT2ARAB9AMAPK1CDK2 | |
| SCHEMBL28056008 | 0.72 | NPC1 (0.72) | NPC1KMT2ARAB9AMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1124811-A1 | 2-UREIDO-THIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS ANTITUMOR AGENTS | PHARMACIA & UPJOHN S.p.A. (IT) | 2001-08-22 | — | — | EP | disclosed |
| WO-2000026203-A1 | 2-UREIDO-THIAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS ANTITUMOR AGENTS | PHARMACIA & UPJOHN S.P.A. (IT) | 2000-05-11 | — | — | WO | disclosed |