Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.46 |
| ▸ | CLEC4M | Q9H2X3 | 1/20 | 0.46 |
| ▸ | JAK2 | O60674 | 2/20 | 0.45 |
| ▸ | JAK3 | P52333 | 2/20 | 0.45 |
| ▸ | FHIT | P49789 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19438592 | 0.84 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AGAAHSD17B10 | |
| SCHEMBL28603667 | 0.81 | MAPT (0.47) | ALDH1A1MEN1KMT2AGAAHSD17B10 | |
| SCHEMBL8203998 | 0.78 | KDM4E (0.46) | ALDH1A1MEN1KMT2AMAPTHPGD | |
| SCHEMBL8032295 | 0.78 | KDM4E (0.48) | ALDH1A1MEN1KMT2AGAAHSD17B10 | |
| SCHEMBL19438586 | 0.76 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AGAAHSD17B10 | |
| SCHEMBL1493615 | 0.76 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2AGAAHSD17B10 | |
| SCHEMBL8061323 | 0.75 | HTT (0.54) | ALDH1A1MEN1KMT2AGAAHSD17B10 | |
| SCHEMBL3267220 | 0.75 | KMT2A (0.56) | ALDH1A1MEN1KMT2AGAAHSD17B10 | |
| Hydrochloric Acid SCHEMBL27223443 | 0.74 | KMT2A (0.55) | ALDH1A1MEN1KMT2AGAAHSD17B10 | |
| SCHEMBL4544350 | 0.74 | SMN1; SMN2 (0.54) | ALDH1A1MEN1KMT2AGAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805812-B1 | BICYCLIC SUBSTITUTED HEXAHYDROBENZ(E)ISOINDOLE ALPHA-1- ADRENERGIC ANTAGONISTS | ABBOTT LAB (US) | 2001-06-13 | — | — | EP | disclosed |
| US-5792767-A | TREATMENT OF BENIGN PROSTATIC HYPERTROPY | ABBOTT LABORATORIES (US) | 1998-08-11 | — | — | US | disclosed |
| EP-0488248-B1 | Cyan image forming method and silver halide color photographic material containing cyan coupler | FUJI PHOTO FILM CO LTD (JP) | 1997-02-26 | — | — | EP | disclosed |
| WO-1996022991-A1 | BICYCLIC SUBSTITUTED HEXAHYDROBENZ[E]ISOINDOLE ALPHA-1- ADRENERGIC ANTAGONISTS | ABBOTT LABORATORIES (US) | 1996-08-01 | — | — | WO | disclosed |
| US-5521181-A | Bicyclic substituted hexahydrobenz[e]isoindole α-1 adrenergic antagonists | ABBOTT LABORATORIES (US) | 1996-05-28 | — | — | US | disclosed |
| US-5270153-A | Cyan image forming method and silver halide color photographic material containing cyan coupler | FUJI PHOTO FILM CO., LTD. (JP) | 1993-12-14 | — | — | US | disclosed |
| EP-0488248-A1 | Cyan image forming method and silver halide color photographic material containing cyan coupler | FUJI PHOTO FILM CO., LTD. (JP) | 1992-06-03 | — | — | EP | disclosed |