SCHEMBL8032295

SCHEMBL8032295

CCOC(=O)c1c(C#N)c[nH]c1N

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 7/20 0.48
HSD17B10 Q99714 2/20 0.48
ALDH1A1 P00352 7/20 0.45
MAPT P10636 5/20 0.45
MEN1 O00255 4/20 0.45
KMT2A Q03164 4/20 0.45
RXFP1 Q9HBX9 2/20 0.45
HPGD P15428 2/20 0.44
GAA P10253 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
POLB P06746 3/20 0.42
HTT P42858 2/20 0.42
RECQL P46063 1/20 0.42
FHIT P49789 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.40
CA12 O43570 1/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4230095 0.83 KDM5A (0.41) KDM4EHSD17B10ALDH1A1MAPTMEN1
SCHEMBL19438592 0.79 ALDH1A1 (0.50) KDM4EHSD17B10ALDH1A1MAPTMEN1
SCHEMBL17221655 0.79 KDM4E (0.48) KDM4EHSD17B10ALDH1A1MAPTMEN1
SCHEMBL7848926 0.78 ALDH1A1 (0.53) HSD17B10ALDH1A1MAPTMEN1KMT2A
SCHEMBL28603667 0.76 MAPT (0.47) HSD17B10ALDH1A1MAPTMEN1KMT2A
SCHEMBL24392515 0.75 ALDH1A1 (0.50) KDM4EHSD17B10ALDH1A1MAPTMEN1
SCHEMBL19438586 0.72 ALDH1A1 (0.42) KDM4EHSD17B10ALDH1A1MAPTMEN1
SCHEMBL3092655 0.71 ALDH1A1 (0.56) KDM4EHSD17B10ALDH1A1MAPTMEN1
SCHEMBL15689404 0.71 KDM4E (0.49) KDM4EHSD17B10ALDH1A1MAPTMEN1
SCHEMBL8061323 0.71 HTT (0.54) KDM4EHSD17B10ALDH1A1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0572029-B1 Silver halide color photographic light-sensitive material FUJI PHOTO FILM CO LTD (JP) 2000-04-12 EP disclosed
EP-0573008-B1 Silver halide color photographic material FUJI PHOTO FILM CO LTD (JP) 1998-11-18 EP disclosed
US-5573898-A PYRROLOAZOLE CYAN DYE-FORMING COUPLER, WATERPROOF RESIN COATING LAYERS, WHITE PIGMENT FUJI PHOTO FILM CO., LTD. (JP) 1996-11-12 US disclosed
US-5547825-A INCLUDES ON THE SUPPORT THE COMBINATION OF A PYRROLOAZOLE TYPE CYAN COUPLER AND A REDOX COMPOUND HAVING A MOLECULAR WEIGHT OF AT LEAST 350; LIGHT FAST REPRODUCTIONS UNDER HIGH AND LOW HUMIDITY FUJI PHOTO FILM CO., LTD. (JP) 1996-08-20 US disclosed
US-5543282-A COLORFASTNESS, STABILITY, FUJI PHOTO FILM CO., LTD. (JP) 1996-08-06 US disclosed
US-5415982-A Pyrroloazoletype cyan coupler, scarcely water soluble epoxy compound FUJI PHOTO FILM CO., LTD. (JP) 1995-05-16 US disclosed
US-5397691-A Rapid processing film and color reproduction FUJI PHOTO FILM CO., LTD. (JP) 1995-03-14 US disclosed
EP-0574948-A1 Silver halide color photographic photosensitive materials FUJI PHOTO FILM CO., LTD. (JP) 1993-12-22 EP disclosed
EP-0573008-A1 Silver halide color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1993-12-08 EP disclosed
EP-0572029-A1 Silver halide color photographic light-sensitive material FUJI PHOTO FILM CO., LTD. (JP) 1993-12-01 EP disclosed