Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HTR3A | P46098 | 2/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | RAD52 | P43351 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.33 |
| ▸ | UGCG | Q16739 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7848965 | 0.81 | MAPK1 (0.41) | MAPTALDH1A1KDM4ELMNAGAA | |
| SCHEMBL30912449 | 0.71 | ALDH1A1 (0.39) | MAPTALDH1A1KDM4ELMNAUSP2 | |
| SCHEMBL30912556 | 0.71 | ALDH1A1 (0.39) | MAPTALDH1A1KDM4ELMNAUSP2 | |
| SCHEMBL3413033 | 0.70 | ALDH1A1 (0.49) | MAPTALDH1A1KDM4ELMNANR4A1 | |
| SCHEMBL6355490 | 0.70 | ALDH1A1 (0.60) | MAPTALDH1A1KDM4ELMNANR4A1 | |
| SCHEMBL10155726 | 0.69 | KDM4E (0.46) | MAPTALDH1A1KDM4ELMNARAD52 | |
| Hydrochloric Acid SCHEMBL6353868 | 0.69 | ALDH1A1 (0.59) | MAPTALDH1A1KDM4ELMNANR4A1 | |
| SCHEMBL4802022 | 0.69 | ALDH1A1 (0.51) | MAPTALDH1A1KDM4ELMNA | |
| SCHEMBL21644440 | 0.69 | ALDH1A1 (0.51) | MAPTALDH1A1KDM4ELMNANR4A1 | |
| SCHEMBL4802029 | 0.69 | ALDH1A1 (0.51) | MAPTALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066288-A2 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 2001-01-10 | — | — | EP | disclosed |
| WO-1999042465-A2 | SULPHONAMIDE DERIVATIVES BEING 5-HT6 RECEPTOR ANTAGONISTS AND PROCESS FOR THEIR PREPARATION | SMITHKLINE BEECHAM PLC (GB) | 1999-08-26 | — | — | WO | disclosed |