Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.38 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.38 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7848968 | 0.81 | MAPT (0.47) | MAPK1ALDH1A1KDM4ELMNAGAA | |
| SCHEMBL6355486 | 0.74 | CTPS1 (0.58) | MAPK1PDE4DPDE4APDE4BPDE4C | |
| Hydrochloric Acid SCHEMBL6353867 | 0.73 | CTPS1 (0.57) | MAPK1PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL1397384 | 0.70 | KDM4E (0.63) | ALDH1A1HSD17B10KDM4ESLC2A1SLC2A2 | |
| SCHEMBL7845695 | 0.70 | MAPK1 (0.48) | MAPK1PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL2779632 | 0.69 | HTR3A (0.59) | MAPK1LMNASLC2A1SLC2A2SLC2A3 | |
| Hydrochloric Acid SCHEMBL6343776 | 0.69 | KDM4E (0.62) | ALDH1A1HSD17B10KDM4ESLC2A1SLC2A2 | |
| Hydrochloric Acid SCHEMBL3072094 | 0.69 | KDM4E (0.62) | ALDH1A1HSD17B10KDM4ESLC2A1SLC2A2 | |
| SCHEMBL7835719 | 0.69 | CHRNA4 (0.47) | MAPK1PDE4DPDE4APDE4BPDE4C | |
| SCHEMBL7035600 | 0.69 | OPRK1 (0.49) | MAPK1SLC2A1SLC2A2SLC2A3HTR1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1066288-A2 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM PLC (GB) | 2001-01-10 | — | — | EP | disclosed |
| WO-1999042465-A2 | SULPHONAMIDE DERIVATIVES BEING 5-HT6 RECEPTOR ANTAGONISTS AND PROCESS FOR THEIR PREPARATION | SMITHKLINE BEECHAM PLC (GB) | 1999-08-26 | — | — | WO | disclosed |