Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1A | P35348 | 20/20 | 0.61 |
| ▸ | ADRA1D | P25100 | 19/20 | 0.61 |
| ▸ | ADRA1B | P35368 | 19/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7852232 | 0.91 | ADRA1A (0.63) | ADRA1AADRA1DADRA1B | |
| SCHEMBL8007922 | 0.87 | ADRA1D (0.62) | ADRA1AADRA1DADRA1B | |
| SCHEMBL8011585 | 0.84 | ADRA1D (0.77) | ADRA1AADRA1DADRA1B | |
| SCHEMBL7996039 | 0.84 | ADRA1D (0.81) | ADRA1AADRA1DADRA1B | |
| SCHEMBL8008470 | 0.84 | ADRA1D (0.81) | ADRA1AADRA1DADRA1B | |
| SCHEMBL8142311 | 0.83 | ADRA1A (0.71) | ADRA1AADRA1DADRA1B | |
| SCHEMBL8142307 | 0.83 | ADRA1A (0.71) | ADRA1AADRA1DADRA1B | |
| Hydrochloric Acid SCHEMBL8147992 | 0.82 | ADRA1A (0.70) | ADRA1AADRA1DADRA1B | |
| SCHEMBL7080849 | 0.82 | ADRA1A (0.64) | ADRA1AADRA1DADRA1B | |
| SCHEMBL7078394 | 0.82 | ADRA1A (0.69) | ADRA1AADRA1DADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1019052-A4 | ALPHA 1A ADRENERGIC RECEPTOR ANTAGONISTS | MERCK & CO INC (US) | 2001-05-16 | — | — | EP | disclosed |
| US-6143750-A | NITROGEN HETEROCYCLIC COMPOUNDS AS ENZYME INHIBITORS, FOR PROSTATE PROBLEMS AND MUSCLE RELAXANTS | MERCK & CO., INC. (US) | 2000-11-07 | — | — | US | disclosed |
| EP-1019052-A1 | ALPHA 1A ADRENERGIC RECEPTOR ANTAGONISTS | Merck & Co., Inc. (US) | 2000-07-19 | — | — | EP | disclosed |
| WO-1998057640-A1 | ALPHA 1A ADRENERGIC RECEPTOR ANTAGONISTS | MERCK & CO., INC. (US) | 1998-12-23 | — | — | WO | disclosed |