SCHEMBL7849083

SCHEMBL7849083

Cc1nc2cnccc2n1CC1CCN(S(=O)(=O)c2cn(OC(=O)O)c3cc(-c4ccc(F)cc4)ccc23)CC1

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PTGER4 P35408 2/20 0.40
PTAFR P25105 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7848370 0.92
SCHEMBL7847305 0.88 HTT (0.46)
SCHEMBL7842644 0.87 CNR2 (0.37) PTGER4PTAFR
SCHEMBL7842338 0.87
SCHEMBL7835077 0.81 HTT (0.43)
SCHEMBL7835013 0.81 TDO2 (0.38) PTAFR
SCHEMBL7846036 0.79
SCHEMBL7844397 0.75 HTT (0.44)
SCHEMBL7847850 0.75 HTT (0.46)
Hydrochloric Acid SCHEMBL7848836 0.74 HTT (0.45)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0821685-B1 INDOLE-3-CARBONYL AND INDOLE-3-SULFONYL DERIVATIVES AS PLATELET ACTIVATING FACTOR ANTAGONISTS ABBOTT LAB (US) 2001-10-04 EP claimed