SCHEMBL7849138

SCHEMBL7849138

CCCCCC(CC)C(C)(C)F

nearest known ligand 0.39

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FDPS P14324 2/20 0.39
OPRM1 P35372 1/20 0.37
LMNA P02545 1/20 0.34
MAPT P10636 1/20 0.34
CA2 P00918 3/20 0.33
DNM1 Q05193 2/20 0.33
CA1 P00915 1/20 0.33
FAAH O00519 1/20 0.32
MAPK1 P28482 1/20 0.32
TSHR P16473 1/20 0.32
THRB P10828 1/20 0.32
GPR84 Q9NQS5 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22624151 0.88 FDPS (0.45) FDPSOPRM1LMNAMAPTCA2
SCHEMBL21970963 0.86 FDPS (0.39) FDPSOPRM1LMNAMAPTCA2
SCHEMBL28320496 0.83 FDPS (0.41) FDPSOPRM1LMNAMAPTDNM1
SCHEMBL22294036 0.82
SCHEMBL19565241 0.82 FDPS (0.43) FDPSOPRM1LMNACA2DNM1
SCHEMBL24118556 0.79
SCHEMBL21217121 0.78 FDPS (0.45) FDPSOPRM1LMNAMAPTCA2
SCHEMBL19997561 0.78 FDPS (0.45) FDPSOPRM1LMNAMAPTCA2
SCHEMBL22162475 0.77 OPRM1 (0.39) FDPSOPRM1LMNAMAPTDNM1
SCHEMBL3802952 0.77 FDPS (0.43) FDPSOPRM1LMNAMAPTDNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2000065801-A9 CYCLOHEXYL- AND CYCLOHEXENYL-SUBSTITUTED LIQUID CRYSTALS WITH LOW BIREFRINGENCE DISPLAYTECH INC (US) 2001-04-12 WO disclosed
WO-2000065801-A1 CYCLOHEXYL- AND CYCLOHEXENYL-SUBSTITUTED LIQUID CRYSTALS WITH LOW BIREFRINGENCE DISPLAYTECH, INC. (US) 2000-11-02 WO disclosed