SCHEMBL7849243

SCHEMBL7849243

CCCCCCc1cccc([Mg]Cl)c1

nearest known ligand 0.57

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LPL P06858 3/20 0.53
LIPG Q9Y5X9 3/20 0.53
HTR2A P28223 1/20 0.46
PPARG P37231 3/20 0.46
PPARA Q07869 3/20 0.46
KCNH2 Q12809 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
GPR3 P46089 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7850223 0.98 LPL (0.51) LPLLIPGHTR2APPARGPPARA
SCHEMBL7849535 0.93 LPL (0.45) LPLLIPGPPARGPPARA
SCHEMBL7852118 0.85 TAAR1 (0.38) LPLLIPG
SCHEMBL5249436 0.81 LPL (0.67) LPLLIPGHTR2APPARGPPARA
SCHEMBL10518886 0.81 LPL (0.67) LPLLIPGHTR2APPARGPPARA
SCHEMBL4032533 0.81 LPL (0.67) LPLLIPGHTR2APPARGPPARA
SCHEMBL6932623 0.81 LPL (0.67) LPLLIPGHTR2APPARGPPARA
SCHEMBL29742685 0.81 LPL (0.67) LPLLIPGHTR2APPARGPPARA
SCHEMBL8563196 0.81 LPL (0.67) LPLLIPGHTR2APPARGPPARA
SCHEMBL27683349 0.81 LPL (0.67) LPLLIPGHTR2APPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0953564-B1 Process for preparing 2-cyanobiphenyl compound SUMIKA FINE CHEMICALS CO LTD (JP) 2001-06-13 EP disclosed
EP-0854135-B1 Process for preparing 2-cyanobiphenyl compound SUMIKA FINE CHEMICALS CO LTD (JP) 2000-02-02 EP disclosed
US-5998652-A Process for preparing 2-cyanobiphenyl compound SUMIKA FINE CHEMICALS CO., LTD. (JP) 1999-12-07 US disclosed
EP-0953564-A1 Process for preparing 2-cyanobiphenyl compound SUMIKA FINE CHEMICALS Co., Ltd. (JP) 1999-11-03 EP disclosed
EP-0854135-A2 Process for preparing 2-cyanobiphenyl compound SUMIKA FINE CHEMICALS Co., Ltd. (JP) 1998-07-22 EP disclosed