Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | CDC25A | P30304 | 1/20 | 0.33 |
| ▸ | CDC25B | P30305 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21666479 | 0.80 | ERN1 (0.33) | ERN1KDM4EMAPTMEN1KMT2A | |
| SCHEMBL7498507 | 0.78 | NQO2 (0.44) | ERN1KDM4EMAPTMEN1POLB | |
| SCHEMBL29655578 | 0.78 | SLC2A1 (0.49) | ERN1KDM4EMAPTMEN1GAA | |
| SCHEMBL18979888 | 0.73 | ERN1 (0.47) | ERN1KDM4EMAPTGAAALDH1A1 | |
| SCHEMBL31429079 | 0.72 | SMN1; SMN2 (0.41) | KDM4EMAPTMEN1GAAKMT2A | |
| SCHEMBL8818184 | 0.69 | ALDH1A1 (0.41) | ERN1KDM4EMAPTMEN1POLB | |
| SCHEMBL30045931 | 0.69 | ALDH1A1 (0.41) | ERN1KDM4EMAPTMEN1POLB | |
| SCHEMBL7857032 | 0.68 | KDM4E (0.48) | KDM4EMAPTMEN1POLBGAA | |
| SCHEMBL19603077 | 0.67 | ERN1 (0.64) | ERN1KDM4EMAPTMEN1POLB | |
| SCHEMBL22902565 | 0.67 | ERN1 (0.42) | ERN1MEN1POLBKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001004130-A1 | PHOSPHORAMIDE COMPOUNDS | PURDUE RESEARCH FOUNDATION (US) | 2001-01-18 | — | — | WO | disclosed |
| WO-1997023456-A1 | INDOLOQUINONE DERIVATIVES AS BIOREDUCTIVE AGENTS | BRITISH TECHNOLOGY GROUP LTD. (GB) | 1997-07-03 | — | — | WO | disclosed |