Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27889099 | 0.78 | LMNA (0.47) | LMNAKDM4EL3MBTL1ALDH1A1GAA | |
| SCHEMBL5809697 | 0.77 | PTGS1 (0.46) | L3MBTL1ALDH1A1MAPT | |
| SCHEMBL7965141 | 0.75 | SLC2A1 (0.54) | LMNAKDM4EL3MBTL1ALDH1A1GAA | |
| SCHEMBL5809599 | 0.73 | ESR1 (0.38) | LMNAKDM4EL3MBTL1HPGDMEN1 | |
| SCHEMBL7849324 | 0.72 | ERN1 (0.36) | KDM4EALDH1A1GAAMAPTMEN1 | |
| SCHEMBL28900180 | 0.72 | STING1 (0.47) | SMN1; SMN2LMNAKDM4EALDH1A1GAA | |
| SCHEMBL18277350 | 0.70 | TSHR (0.50) | SMN1; SMN2LMNAKDM4EL3MBTL1ALDH1A1 | |
| SCHEMBL7498507 | 0.69 | NQO2 (0.44) | LMNAKDM4EL3MBTL1ALDH1A1GAA | |
| SCHEMBL29655578 | 0.69 | SLC2A1 (0.49) | KDM4EALDH1A1GAAHSD17B10MAPT | |
| SCHEMBL856590 | 0.69 | LMNA (0.46) | SMN1; SMN2LMNAKDM4EGAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119350333-A | NQO1 agonist based on evodiamine and preparation method and application thereof | 陕西中医药大学 | 2025-01-24 | — | — | CN | disclosed |