Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.42 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4834584 | 0.83 | MAOA (0.45) | MAOAMAOBKDM4EALDH1A1MAPT | |
| SCHEMBL25523507 | 0.82 | CYP1A2 (0.53) | TLR8TLR7ELANEKDM4EALDH1A1 | |
| SCHEMBL29632453 | 0.76 | MAOA (0.45) | MAOAMAOBKDM4EALDH1A1MAPT | |
| SCHEMBL9315070 | 0.73 | MAOA (0.45) | ELANEMAOAMAOBKDM4EALDH1A1 | |
| SCHEMBL7835430 | 0.72 | PDE4A (0.45) | TLR8TLR7ELANEMAOAMAOB | |
| SCHEMBL12386870 | 0.72 | KDM4E (0.50) | TLR8TLR7ELANEMAOAMAOB | |
| SCHEMBL27961872 | 0.71 | MAOA (0.41) | TLR8TLR7ELANEMAOAMAOB | |
| SCHEMBL5573487 | 0.70 | ALDH1A1 (0.47) | TLR8TLR7KDM4EALDH1A1MAPT | |
| SCHEMBL14128989 | 0.70 | KDM4E (0.60) | ELANEMAOAMAOBKDM4EALDH1A1 | |
| SCHEMBL3457627 | 0.70 | SOS1 (0.34) | MAOAMAOBMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117945995-A | Alkylated nitrogen-containing heterocyclic compound and preparation method and application thereof | 中国科学院青海盐湖研究所 | 2024-04-30 | — | — | CN | disclosed |
| EP-0498723-B1 | Nitrogen containing bicycle compounds, method for their preparation, their use as pharmaceutical and compositions containing them | AVENTIS PHARMA SA (FR) | 2001-09-19 | — | — | EP | disclosed |
| EP-0498722-B1 | Bicyclic nitrogen compounds, their preparation, intermediates obtained, their use as pharmaceuticals and pharmaceutical compositions containing them | ROUSSEL UCLAF (FR) | 1997-07-30 | — | — | EP | disclosed |
| EP-0498723-A1 | Nitrogen containing bicycle compounds, method for their preparation, their use as pharmaceutical and compositions containing them | ROUSSEL UCLAF (FR) | 1992-08-12 | — | — | EP | disclosed |
| EP-0498722-A1 | Bicyclic nitrogen compounds, their preparation, intermediates obtained, their use as pharmaceuticals and pharmaceutical compositions containing them | ROUSSEL UCLAF (FR) | 1992-08-12 | — | — | EP | disclosed |