SCHEMBL784945

SCHEMBL784945

CC(C)(C)c1cc(CNc2ccc(Nc3ccc(Nc4ccccc4)cc3)cc2)cc(C(C)(C)C)c1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.50
MEN1 O00255 2/20 0.50
KMT2A Q03164 2/20 0.50
GSR P00390 2/20 0.48
SCN2A Q99250 2/20 0.43
HIF1A Q16665 5/20 0.43
HTT P42858 1/20 0.42
ALDH1A1 P00352 2/20 0.41
LMNA P02545 2/20 0.41
TSHR P16473 2/20 0.41
MAOB P27338 1/20 0.41
MAPK1 P28482 2/20 0.41
NPSR1 Q6W5P4 2/20 0.41
GMNN O75496 1/20 0.41
GABBR2 O75899 1/20 0.41
TP53 P04637 1/20 0.41
CYP1A2 P05177 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
ALOX15 P16050 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL784975 1.00 GAA (0.50) GAAMEN1KMT2AGSRSCN2A
SCHEMBL784941 1.00 GAA (0.50) GAAMEN1KMT2AGSRSCN2A
SCHEMBL14493851 1.00 GAA (0.50) GAAMEN1KMT2AGSRSCN2A
SCHEMBL12377559 0.96 MEN1 (0.47) GAAMEN1KMT2AGSRSCN2A
SCHEMBL29015812 0.94 GSR (0.53) GAAMEN1KMT2AGSRSCN2A
SCHEMBL2741253 0.92 MEN1 (0.43) GAAMEN1KMT2AGSRSCN2A
SCHEMBL16471746 0.92 GAA (0.46) GAAMEN1KMT2AGSRSCN2A
SCHEMBL2783563 0.92 MEN1 (0.43) GAAMEN1KMT2AGSRSCN2A
SCHEMBL2783560 0.92 MEN1 (0.43) GAAMEN1KMT2AGSRSCN2A
SCHEMBL2783561 0.92 MEN1 (0.43) GAAMEN1KMT2AGSRSCN2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9523060-B2 Lubricant oil compositions POLNOX CORPORATION (US) 2016-12-20 US disclosed
US-9523060-B2 Lubricant oil compositions POLNOX CORPORATION (US) 2016-12-20 US disclosed
US-9388120-B2 Nitrogen and hindered phenol containing dual functional macromolecular antioxidants: synthesis, performances and applications POLNOX CORPORATION (US) 2016-07-12 US disclosed
US-20150159109-A1 Lubricant Oil Compositions POLNOX CORPORATION 2015-06-11 US disclosed
US-20150159109-A1 Lubricant Oil Compositions POLNOX CORPORATION 2015-06-11 US disclosed
US-8927472-B2 Lubricant oil compositions POLNOX CORPORATION (US) 2015-01-06 US disclosed
US-8927472-B2 Lubricant oil compositions POLNOX CORPORATION (US) 2015-01-06 US disclosed
US-20140316163-A1 NITROGEN AND HINDERED PHENOL CONTAINING DUAL FUNCTIONAL MACROMOLECULAR ANTIOXIDANTS: SYNTHESIS, PERFORMANCES AND APPLICATIONS POLNOX CORPORATION (US) 2014-10-23 US disclosed
US-8691933-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2014-04-08 US disclosed
US-8691933-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2014-04-08 US disclosed
US-20100305251-A1 STABILIZED POLYOLEFIN COMPOSITIONS POLNOX CORPORATION 2010-12-02 US disclosed
US-20100305251-A1 STABILIZED POLYOLEFIN COMPOSITIONS POLNOX CORPORATION 2010-12-02 US disclosed
US-7705075-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2010-04-27 US disclosed
US-20080293856-A1 Stabilized polyolefin compositions POLNOX CORPORATION 2008-11-27 US disclosed
US-20070161522-A1 Lubricant oil compositions POLNOX CORPORATION 2007-07-12 US disclosed
US-20070161522-A1 Lubricant oil compositions POLNOX CORPORATION 2007-07-12 US disclosed
US-20070149660-A1 Stabilized polyolefin compositions POLNOX CORPORATION 2007-06-28 US disclosed
US-20070149660-A1 Stabilized polyolefin compositions POLNOX CORPORATION 2007-06-28 US disclosed
WO-2007064843-A1 LUBRICANT OIL COMPOSITIONS POLNOX CORPORATION (US) 2007-06-07 WO disclosed
WO-2007050991-A1 STABILIZED POLYOLEFIN COMPOSITIONS POLNOX CORPORATION (US) 2007-05-03 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140316163-A1 NITROGEN AND HINDERED PHENOL CONTAINING DUAL FUNCTIONAL MACROMOLECULAR ANTIOXIDANTS: SYNTHESIS, PERFORMANCES AND APPLICATIONS CAT, LPO, DUOX1 GAA 1057/4885MEN1 4853/4885KMT2A 4126/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.