Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.46 |
| ▸ | CCR8 | P51685 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | TGFBR1 | P36897 | 13/20 | 0.43 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR1D | P28221 | 1/20 | 0.38 |
| ▸ | HTR1B | P28222 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7847744 | 0.86 | KDM4E (0.56) | CCR1CCR8KDM4EALDH1A1HPGD | |
| SCHEMBL6609571 | 0.78 | ALDH1A1 (0.58) | CCR1CCR8KDM4EALDH1A1HPGD | |
| SCHEMBL7846725 | 0.78 | CD38 (0.37) | KDM4EALDH1A1HPGD | |
| SCHEMBL2153429 | 0.75 | ALDH1A1 (0.52) | KDM4EALDH1A1HPGDCYP2A6 | |
| SCHEMBL12270088 | 0.74 | CCR1 (0.58) | CCR1CCR8KDM4EALDH1A1HPGD | |
| SCHEMBL11436575 | 0.73 | NR4A1 (0.52) | KDM4EALDH1A1HPGD | |
| SCHEMBL27887898 | 0.73 | CDC25B (0.50) | KDM4EALDH1A1HPGDHTR1AHTR1D | |
| SCHEMBL27573254 | 0.71 | CCR1 (0.48) | CCR1CCR8KDM4EALDH1A1HPGD | |
| SCHEMBL15945853 | 0.69 | CCR1 (0.56) | CCR1CCR8TGFBR1CYP2A6 | |
| SCHEMBL16003830 | 0.69 | PDE10A (0.47) | CCR1CCR8KDM4EALDH1A1TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140946-A2 | QUINOLINE DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035919-A2 | QUINOLINE DERIVATIVES | SMITHKLINE BEECHAM PLC (GB) | 2000-06-22 | — | — | WO | disclosed |