Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TSPO | P30536 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 2/20 | 0.30 |
| ▸ | RAB9A | P51151 | 2/20 | 0.30 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.30 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.30 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7849230 | 0.81 | SMN1; SMN2 (0.40) | SMN1; SMN2ALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL2536208 | 0.80 | ALDH1A1 (0.43) | SMN1; SMN2TSPOALDH1A1L3MBTL1NPC1 | |
| SCHEMBL7849505 | 0.79 | HTR2C (0.40) | OPRM1SMN1; SMN2TSPOALDH1A1MEN1 | |
| Phenylacetylglycine Dimethylamide SCHEMBL6056919 | 0.75 | ALDH1A1 (0.49) | OPRM1OPRL1SMN1; SMN2TSPOALDH1A1 | |
| SCHEMBL7849283 | 0.75 | ALDH1A1 (0.36) | OPRM1OPRL1SMN1; SMN2ALDH1A1NR4A1 | |
| SCHEMBL95841 | 0.74 | ALDH1A1 (0.39) | OPRM1OPRL1SMN1; SMN2TSPOALDH1A1 | |
| SCHEMBL7801492 | 0.74 | ALDH1A1 (0.44) | ALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL2538996 | 0.72 | ALDH1A1 (0.44) | OPRM1TSPOALDH1A1NPC1RAB9A | |
| SCHEMBL7839570 | 0.72 | KDM4E (0.38) | ALDH1A1NPC1RAB9ANR4A1KMT2A | |
| SCHEMBL3120587 | 0.72 | GAA (0.41) | OPRM1OPRL1SMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1115704-A1 | NOVEL SUBSTITUTED INDOLINONES WITH AN INHIBITORY EFFECT ON VARIOUS KINASES AND CYCLIN/CDK COMPLEXES | Boehringer Ingelheim Pharma KG (DE) | 2001-07-18 | — | — | EP | disclosed |
| WO-2000018734-A1 | NOVEL SUBSTITUTED INDOLINONES WITH AN INHIBITORY EFFECT ON VARIOUS KINASES AND CYCLIN/CDK COMPLEXES | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-04-06 | — | — | WO | disclosed |