Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPI | P09923 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.50 |
| ▸ | XIAP | P98170 | 1/20 | 0.50 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.50 |
| ▸ | MC4R | P32245 | 4/20 | 0.48 |
| ▸ | MC5R | P33032 | 3/20 | 0.48 |
| ▸ | MC3R | P41968 | 3/20 | 0.48 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.43 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.41 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.41 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.41 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.41 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.41 |
| ▸ | ANPEP | P15144 | 1/20 | 0.40 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.40 |
| ▸ | DNPEP | Q9ULA0 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29641523 | 0.90 | SLC7A5 (0.52) | SLC7A5MC4RMC5RMC3RITGB3 | |
| SCHEMBL29909939 | 0.90 | SLC7A5 (0.52) | SLC7A5MC4RMC5RMC3RITGB3 | |
| SCHEMBL7907904 | 0.90 | ALPI (0.50) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL7857948 | 0.89 | ITGB3 (0.41) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL8174915 | 0.83 | MC4R (0.47) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL29641630 | 0.83 | ITGB3 (0.50) | MC4RMC5RMC3RITGB3ITGA2B | |
| SCHEMBL7857054 | 0.83 | MMP2 (0.50) | MC4RMC5RMC3RMMP2SLC1A2 | |
| SCHEMBL29641711 | 0.83 | ITGB3 (0.50) | MC4RMC5RMC3RITGB3ITGA2B | |
| SCHEMBL27920904 | 0.83 | MC4R (0.52) | ALPIPKMPTGS1XIAPSLC7A5 | |
| SCHEMBL27920888 | 0.83 | MC4R (0.52) | ALPIPKMPTGS1XIAPSLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6245746-B1 | ADMINISTERING AMIDE MICROBIOCIDE ANTIBIOTIC | MICROCIDE PHARMACEUTICALS, INC. | 2001-06-12 | — | — | US | disclosed |
| US-6114310-A | THERAPY FOR MICROBIAL INFECTIONS | MICROCIDE PHARMACEUTICALS, INC. (US) | 2000-09-05 | — | — | US | disclosed |