Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.51 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.51 |
| ▸ | P2RY6 | Q15077 | 12/20 | 0.50 |
| ▸ | DRD5 | P21918 | 3/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5566272 | 0.76 | P2RY6 (0.47) | PTGS2PTGS1P2RY6DRD5ADRA2A | |
| SCHEMBL1930991 | 0.72 | P2RY6 (0.41) | P2RY6 | |
| SCHEMBL5565980 | 0.69 | PTGS2 (0.45) | PTGS2PTGS1P2RY6 | |
| SCHEMBL6092204 | 0.68 | PTGS2 (1.00) | PTGS2PTGS1P2RY6 | |
| SCHEMBL6092198 | 0.68 | PTGS2 (1.00) | PTGS2PTGS1P2RY6 | |
| SCHEMBL6439719 | 0.68 | RORC (0.36) | CA12CA9 | |
| SCHEMBL7849593 | 0.65 | PTGS2 (0.35) | PTGS2PTGS1 | |
| SCHEMBL9088717 | 0.64 | — | — | |
| SCHEMBL6022329 | 0.63 | PTGS2 (0.52) | PTGS2PTGS1 | |
| SCHEMBL5565731 | 0.62 | PTGS2 (0.48) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1123285-A1 | SUBSTITUTED BENZOPYRAN ANALOGS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 2001-08-16 | — | — | EP | disclosed |
| WO-2000023433-A1 | SUBSTITUTED BENZOPYRAN ANALOGS FOR THE TREATMENT OF INFLAMMATION | G.D. SEARLE & CO. (US) | 2000-04-27 | — | — | WO | disclosed |