Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 14/20 | 0.59 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KDM6B | O15054 | 1/20 | 0.41 |
| ▸ | KDM6A | O15550 | 1/20 | 0.41 |
| ▸ | TET3 | O43151 | 1/20 | 0.41 |
| ▸ | KDM4A | O75164 | 1/20 | 0.41 |
| ▸ | KDM4B | O94953 | 1/20 | 0.41 |
| ▸ | KDM5C | P41229 | 1/20 | 0.41 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.41 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.41 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.41 |
| ▸ | TET1 | Q8NFU7 | 1/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7852137 | 0.91 | TACR1 (0.56) | TACR1SMN1; SMN2KDM4E | |
| SCHEMBL7849465 | 0.90 | TACR1 (0.63) | TACR1GRIA2GRIA4 | |
| Hydrochloric Acid SCHEMBL7852820 | 0.90 | TACR1 (0.66) | TACR1GRIA2GRIA4 | |
| SCHEMBL7854807 | 0.89 | TACR1 (0.48) | TACR1PADI4LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL7849658 | 0.88 | TACR1 (0.54) | TACR1KMT2AKDM4EGRIA2GRIA4 | |
| Hydrochloric Acid SCHEMBL7852917 | 0.87 | TACR1 (0.52) | TACR1KMT2AGRIA2GRIA4 | |
| SCHEMBL7854819 | 0.82 | TACR1 (0.55) | TACR1LMNAKMT2AEGLN1L3MBTL1 | |
| SCHEMBL8784770 | 0.81 | TACR1 (0.55) | TACR1LMNAKMT2ASMN1; SMN2GRIA2 | |
| SCHEMBL7850548 | 0.80 | TACR1 (0.63) | TACR1SMN1; SMN2KDM4E | |
| SCHEMBL7841672 | 0.80 | TACR1 (0.52) | TACR1GRIA2GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0652218-B1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-07-11 | — | — | EP | disclosed |
| US-5585385-A | USEFUL IN TREATING DISORDERS OF MICTURITION; ADMINISTERING TO INHIBIT PLASMA EXTRAVASATION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-17 | — | — | US | disclosed |
| EP-0652218-A1 | Heterocyclic compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1995-05-10 | — | — | EP | disclosed |