Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 13/20 | 0.54 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.45 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | SLC11A2 | P49281 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7852343 | 0.90 | TACR1 (0.53) | TACR1KMT2AKAT2BKDM4EUSP2 | |
| SCHEMBL7850487 | 0.88 | TACR1 (0.59) | TACR1GRIA2GRIA4KMT2AKDM4E | |
| SCHEMBL7852137 | 0.87 | TACR1 (0.56) | TACR1KAT2BKDM4EHPGD | |
| Hydrochloric Acid SCHEMBL7852820 | 0.86 | TACR1 (0.66) | TACR1GRIA2GRIA4 | |
| SCHEMBL7849465 | 0.86 | TACR1 (0.63) | TACR1GRIA2GRIA4 | |
| SCHEMBL7855252 | 0.79 | TACR1 (0.43) | TACR1KMT2AMEN1KAT2BKDM4E | |
| Hydrochloric Acid SCHEMBL7852917 | 0.78 | TACR1 (0.52) | TACR1GRIA2GRIA4KMT2A | |
| SCHEMBL7854807 | 0.78 | TACR1 (0.48) | TACR1GRIA2GRIA4KMT2AKDM4E | |
| SCHEMBL6636299 | 0.77 | PADI4 (0.47) | KMT2AKAT2BKDM4EUSP2ALDH1A1 | |
| SCHEMBL7850548 | 0.76 | TACR1 (0.63) | TACR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0652218-B1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-07-11 | — | — | EP | disclosed |
| US-5585385-A | USEFUL IN TREATING DISORDERS OF MICTURITION; ADMINISTERING TO INHIBIT PLASMA EXTRAVASATION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-17 | — | — | US | disclosed |
| EP-0652218-A1 | Heterocyclic compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1995-05-10 | — | — | EP | disclosed |