SCHEMBL7850495

SCHEMBL7850495

O=Cc1cccc(-c2ccccn2)c1O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ERN1 O75460 7/20 0.49
GRM5 P41594 2/20 0.44
LMNA P02545 3/20 0.42
KDM4E B2RXH2 3/20 0.42
CCR1 P32246 2/20 0.42
CCR5 P51681 2/20 0.42
CCR8 P51685 2/20 0.42
BLM P54132 2/20 0.42
CYP1A2 P05177 1/20 0.42
POLB P06746 1/20 0.42
METAP1 P53582 1/20 0.42
HIF1A Q16665 1/20 0.42
DOHH Q9BU89 1/20 0.42
P4HTM Q9NXG6 1/20 0.42
KDM1A O60341 3/20 0.41
TRIM24 O15164 2/20 0.41
TRIM33 Q9UPN9 2/20 0.41
TDP1 Q9NUW8 2/20 0.41
HSP90AA1 P07900 2/20 0.41
L3MBTL1 Q9Y468 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30062580 0.84 KDM4E (0.50) ERN1GRM5LMNAKDM4ECCR1
SCHEMBL29823771 0.84 KDM4E (0.50) ERN1GRM5LMNAKDM4ECCR1
SCHEMBL893835 0.84 KDM4E (0.50) ERN1GRM5LMNAKDM4ECCR1
Hydrochloric Acid SCHEMBL19893873 0.82 KDM4E (0.48) ERN1GRM5LMNAKDM4ECCR1
SCHEMBL23295096 0.82 ERN1 (0.46) ERN1KDM4ETRIM24TRIM33HSP90AA1
SCHEMBL2734583 0.82 KDM4E (0.56) LMNAKDM4ECCR1CCR5CCR8
SCHEMBL6892647 0.81 KDM1A (0.40) ERN1LMNAKDM4ECCR1CCR5
SCHEMBL1031569 0.80 TRIM24 (0.49) ERN1GRM5LMNAKDM4ECCR1
SCHEMBL4538546 0.80 GRM5 (0.44) ERN1GRM5LMNAKDM4ECCR1
SCHEMBL11066745 0.80 GRM5 (0.44) ERN1GRM5LMNAKDM4ECCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0652216-B1 Substituted Pyridyl salicylic aldehyde and salicylic acid derivatives, methods for preparing them and their use as herbicides BASF AG (DE) 2001-02-28 EP claimed
US-5783521-A Substituted pyridylsalicylaldehyde or -salicylic acid derivatives, their preparation and their use as herbicides BASF AKTIENGESELLSCHAFT (DE) 1998-07-21 US claimed
US-5783521-A Substituted pyridylsalicylaldehyde or -salicylic acid derivatives, their preparation and their use as herbicides BASF AKTIENGESELLSCHAFT (DE) 1998-07-21 US disclosed
US-5783521-A Substituted pyridylsalicylaldehyde or -salicylic acid derivatives, their preparation and their use as herbicides BASF AKTIENGESELLSCHAFT (DE) 1998-07-21 US disclosed
US-5783521-A Substituted pyridylsalicylaldehyde or -salicylic acid derivatives, their preparation and their use as herbicides BASF AKTIENGESELLSCHAFT (DE) 1998-07-21 US disclosed
CN-1107846-A Substituted pyridylsalicylaldehyde or salicylic acid derivatives, their preparation and their use as herbicides BASF AG (DE) 1995-09-06 CN disclosed
CN-1107846-A Substituted pyridylsalicylaldehyde or salicylic acid derivatives, their preparation and their use as herbicides BASF AG (DE) 1995-09-06 CN disclosed
CN-1107846-A Substituted pyridylsalicylaldehyde or salicylic acid derivatives, their preparation and their use as herbicides BASF AG (DE) 1995-09-06 CN disclosed
EP-0652216-A2 Substituted Pyridyl salicylic aldehyde and salicylic acid derivatives, methods for preparing them and their use as herbicides BASF Aktiengesellschaft (DE) 1995-05-10 EP disclosed