Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | CCR1 | P32246 | 2/20 | 0.50 |
| ▸ | CCR5 | P51681 | 2/20 | 0.50 |
| ▸ | CCR8 | P51685 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | METAP1 | P53582 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.50 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.50 |
| ▸ | GRM5 | P41594 | 2/20 | 0.49 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.47 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29823771 | 1.00 | KDM4E (0.50) | KDM4ELMNABLMCCR1CCR5 | |
| SCHEMBL30062580 | 1.00 | KDM4E (0.50) | KDM4ELMNABLMCCR1CCR5 | |
| Hydrochloric Acid SCHEMBL19893873 | 0.98 | KDM4E (0.48) | KDM4ELMNABLMCCR1CCR5 | |
| SCHEMBL1031569 | 0.84 | TRIM24 (0.49) | KDM4ELMNABLMCCR1CCR5 | |
| SCHEMBL4658764 | 0.84 | TRIM24 (0.44) | KDM4ELMNABLMCCR1CCR5 | |
| SCHEMBL11066745 | 0.84 | GRM5 (0.44) | KDM4ELMNABLMCCR1CCR5 | |
| SCHEMBL4538546 | 0.84 | GRM5 (0.44) | KDM4ELMNABLMCCR1CCR5 | |
| SCHEMBL7850495 | 0.84 | ERN1 (0.49) | KDM4ELMNABLMCCR1CCR5 | |
| SCHEMBL27589898 | 0.82 | CDK4 (0.46) | KDM4ELMNABLMCCR1CCR5 | |
| SCHEMBL8498483 | 0.80 | ERN1 (0.49) | KDM4ELMNABLMCCR1CCR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 109 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115043737-A | Tetrahydroarylo secondary amine compound, preparation method and weeding application thereof | 中国林业科学研究院林产化学工业研究所 | 2022-09-13 | — | — | CN | claimed |
| CN-113416173-A | Method for catalytically synthesizing benzothiazole compounds by using copper complexes | 上海应用技术大学 | 2021-09-21 | — | — | CN | claimed |
| CN-111187220-A | Trifluoromethyl pyrimidine derivative containing Schiff base structural unit and preparation method and application thereof | 郑州大学 | 2020-05-22 | — | — | CN | claimed |
| US-20030176709-A1 | Vinyl-phenyl pyridine monomers and polymers prepared thereform | KWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY | 2003-09-18 | — | — | US | claimed |
| US-6545159-B2 | Suzuki coupling reaction of vinyl-phenylboronic acid and 2-bromopyridine in presence of alkali metallic base and tetrakis/triphenylphosphine/palladium to form styrenepyridine monomer | KWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) | 2003-04-08 | — | — | US | claimed |
| US-20020198346-A1 | Vinyl-phenyl pyridine monomers and polymers prepared thereform | KWANGJU INSTITUTE OF SCIENCE AND TECHNOLOGY | 2002-12-26 | — | — | US | claimed |
| EP-0513149-B1 | PYRIDYLPHENYL NITROGEN HETEROCYCLE-SUBSTITUTED CARBINOLS AND DERIVATIVES THEREOF WITH ANTI-INFLAMMATORY ACTIVITY | DU PONT MERCK PHARMA (US) | 1995-12-13 | — | — | EP | claimed |
| US-5250517-A | Hypotensive and cardiotonic agents; cardiac insufficiency | HOFFMANN-LA ROCHE INC. (US) | 1993-10-05 | — | — | US | claimed |
| EP-0513149-A1 | PYRIDYLPHENYL NITROGEN HETEROCYCLE-SUBSTITUTED CARBINOLS AND DERIVATIVES THEREOF WITH ANTI-INFLAMMATORY ACTIVITY. | DU PONT MERCK PHARMA (US) | 1992-11-19 | — | — | EP | claimed |
| WO-1991011445-A1 | PYRIDYLPHENYL NITROGEN HETEROCYCLE-SUBSTITUTED CARBINOLS AND DERIVATIVES THEREOF WITH ANTI-INFLAMMATORY ACTIVITY | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1991-08-08 | — | — | WO | claimed |
| CN-116143751-B | Quinoxalinone compound containing styrylpyridine and preparation method thereof | 中国人民解放军军事科学院防化研究院 | 2025-07-15 | — | — | CN | disclosed |
| WO-2024112731-A1 | FLAVONES, QUINOLINONES, QUINAZOLINONES, AND AURONES, AND USES IN CK2-MEDIATED DISEASES | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2024-05-30 | — | — | WO | disclosed |
| CN-115093410-B | Preparation method of beta-carboline compound | 南京工业大学 | 2023-09-26 | — | — | CN | disclosed |
| CN-116143751-A | Quinoxalinone compound containing styrylpyridine and preparation method thereof | 中国人民解放军军事科学院防化研究院 | 2023-05-23 | — | — | CN | disclosed |
| CN-113956256-B | Matrine D ring structure modified derivative and application thereof in preparation of antitumor drugs | 常州大学 | 2022-11-01 | — | — | CN | disclosed |
| WO-2001027083-A1 | PROCESS FOR THE PREPARATION OF ARYL-PYRIDINYL COMPOUNDS | EUTICALS PRIME EUROPEAN THERAPEUTICAL SPA (IT) | 2001-04-19 | — | — | WO | disclosed |
| EP-0513149-B1 | PYRIDYLPHENYL NITROGEN HETEROCYCLE-SUBSTITUTED CARBINOLS AND DERIVATIVES THEREOF WITH ANTI-INFLAMMATORY ACTIVITY | DU PONT MERCK PHARMA (US) | 1995-12-13 | — | — | EP | disclosed |
| EP-0513149-A1 | PYRIDYLPHENYL NITROGEN HETEROCYCLE-SUBSTITUTED CARBINOLS AND DERIVATIVES THEREOF WITH ANTI-INFLAMMATORY ACTIVITY. | DU PONT MERCK PHARMA (US) | 1992-11-19 | — | — | EP | disclosed |
| US-5049570-A | Pyridylphenyl nitrogen heterocycle-substituted carbinols and derivatives thereof with anti-inflammatory activity | DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1991-09-17 | — | — | US | disclosed |
| WO-1991011445-A1 | PYRIDYLPHENYL NITROGEN HETEROCYCLE-SUBSTITUTED CARBINOLS AND DERIVATIVES THEREOF WITH ANTI-INFLAMMATORY ACTIVITY | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1991-08-08 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020198346-A1 | Vinyl-phenyl pyridine monomers and polymers prepared thereform | VAT1, PBRM1, THEM6 | KDM4E 1455/4885LMNA 4034/4885BLM 4458/4885 |
| US-20030176709-A1 | Vinyl-phenyl pyridine monomers and polymers prepared thereform | VAT1, PBRM1, THEM6 | KDM4E 1455/4885LMNA 4034/4885BLM 4458/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.