Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 3/20 | 0.62 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.62 |
| ▸ | PPARG | P37231 | 6/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7851373 | 0.90 | AGTR1 (0.75) | AGTR1AGTR2PPARG | |
| SCHEMBL10439197 | 0.88 | AGTR1 (0.55) | AGTR1AGTR2 | |
| SCHEMBL7852258 | 0.88 | AGTR1 (0.57) | AGTR1AGTR2PPARG | |
| SCHEMBL8913133 | 0.87 | ALDH1A1 (0.50) | AGTR1AGTR2ALDH1A1ENPP2 | |
| SCHEMBL9195616 | 0.87 | AGTR1 (0.80) | AGTR1AGTR2PPARG | |
| SCHEMBL7843237 | 0.86 | AGTR1 (0.58) | AGTR1AGTR2PPARG | |
| SCHEMBL7851469 | 0.86 | AGTR1 (0.62) | AGTR1AGTR2PPARG | |
| SCHEMBL7851885 | 0.86 | AGTR1 (0.56) | AGTR1AGTR2PPARG | |
| SCHEMBL7850660 | 0.86 | ALDH1A1 (0.64) | AGTR1AGTR2ALDH1A1ENPP2 | |
| SCHEMBL9571416 | 0.84 | ALDH1A1 (0.49) | AGTR1AGTR2ALDH1A1ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0399731-B2 | Azaindenes | ASTRAZENECA AB (SE) | 2001-07-11 | — | — | EP | disclosed |
| US-5470867-A | Imidazoles and their salts having antagonistic activity to angiotesin II recetors | ROUSSEL-UCLAF (FR) | 1995-11-28 | — | — | US | disclosed |
| US-5338756-A | Angiotensin II receptor antagonists | ROUSSEL UCLAF (FR) | 1994-08-16 | — | — | US | disclosed |
| EP-0399731-B1 | Azaindenes | ZENECA LTD (GB) | 1993-12-08 | — | — | EP | disclosed |
| EP-0399731-A1 | Azaindenes | ZENECA LIMITED (GB) | 1990-11-28 | — | — | EP | disclosed |