Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | SNCA | P37840 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RHOA | P61586 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9212901 | 0.80 | SIRT2 (0.40) | CYP3A4ALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL175786 | 0.79 | SNCA (0.67) | CYP3A4SNCAALDH1A1HSD17B10TSHR | |
| SCHEMBL671053 | 0.77 | CA12 (0.53) | CYP3A4ALDH1A1TSHRKDM4ETP53 | |
| SCHEMBL254063 | 0.75 | CYP3A4 (0.59) | CYP3A4SNCAALDH1A1HSD17B10TSHR | |
| Hydrochloric Acid SCHEMBL27813064 | 0.75 | CA12 (0.52) | CYP3A4ALDH1A1TSHRKDM4ETP53 | |
| Benzene SCHEMBL28207781 | 0.74 | CYP3A4 (0.69) | CYP3A4SNCAALDH1A1HSD17B10TSHR | |
| SCHEMBL28343462 | 0.74 | CYP3A4 (0.69) | CYP3A4SNCAALDH1A1HSD17B10TSHR | |
| SCHEMBL17386391 | 0.74 | SNCA (0.61) | CYP3A4SNCAALDH1A1HSD17B10TSHR | |
| SCHEMBL461801 | 0.74 | SNCA (0.61) | CYP3A4SNCAALDH1A1HSD17B10TSHR | |
| SCHEMBL21007 | 0.74 | CYP3A4 (0.69) | CYP3A4SNCAALDH1A1HSD17B10TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5306443-A | Dissolving monomer with metal containing oxidizing agent in sufficient solvent to prevent polymerization; removal of solvent | NIPPON SODA CO., LTD. (JP) | 1994-04-26 | — | — | US | claimed |
| CN-121136320-A | Preparation method of graphene-based antistatic plastic and graphene-based antistatic plastic pipe | 江苏吉庆管材集团有限公司 | 2025-12-16 | — | — | CN | disclosed |
| US-11712467-B2 | Methods of rational nicotine hapten design and uses thereof | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2023-08-01 | — | — | US | disclosed |
| US-11712467-B2 | Methods of rational nicotine hapten design and uses thereof | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2023-08-01 | — | — | US | disclosed |
| US-11712467-B2 | Methods of rational nicotine hapten design and uses thereof | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2023-08-01 | — | — | US | disclosed |
| US-20220362375-A1 | METHODS OF RATIONAL NICOTINE HAPTEN DESIGN AND USES THEREOF | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-11-17 | — | — | US | disclosed |
| US-11357848-B2 | Methods of rational nicotine hapten design and uses thereof | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2022-06-14 | — | — | US | disclosed |
| US-11357848-B2 | Methods of rational nicotine hapten design and uses thereof | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) | 2022-06-14 | — | — | US | disclosed |
| US-20180125969-A1 | METHODS OF RATIONAL NICOTINE HAPTEN DESIGN AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2018-05-10 | — | — | US | disclosed |
| US-20180125969-A1 | METHODS OF RATIONAL NICOTINE HAPTEN DESIGN AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2018-05-10 | — | — | US | disclosed |
| US-5869485-A | Pyrrolo 2,3-d!pyrimidines and their use | NOVARTIS FINANCE CORP. (US) | 1999-02-09 | — | — | US | disclosed |
| EP-0783505-A1 | PYRROLO[2,3-d]PYRIMIDINES AND THEIR USE | Novartis AG (CH) | 1997-07-16 | — | — | EP | disclosed |
| WO-1996010028-A1 | PYRROLO[2,3-d]PYRIMIDINES AND THEIR USE | NOVARTIS AG (CH) | 1996-04-04 | — | — | WO | disclosed |
| EP-0332704-B1 | PROCESS FOR PRODUCING CONDUCTIVE POLYMER FILM | NIPPON SODA CO (JP) | 1994-12-21 | — | — | EP | disclosed |
| US-5306443-A | Dissolving monomer with metal containing oxidizing agent in sufficient solvent to prevent polymerization; removal of solvent | NIPPON SODA CO., LTD. (JP) | 1994-04-26 | — | — | US | disclosed |
| EP-0332704-A1 | PROCESS FOR PRODUCING CONDUCTIVE POLYMER FILM | NIPPON SODA CO., LTD. (JP) | 1989-09-20 | — | — | EP | disclosed |
| US-4511575-A | Antidiabetic pyrrolecarboxylic acids | PFIZER INC. (US) | 1985-04-16 | — | — | US | disclosed |
| US-4511576-A | Antidiabetic pyrrolecarboxylic acids | PFIZER INC. (US) | 1985-04-16 | — | — | US | disclosed |
| US-4351843-A | LOWERING BLOOD GLUCOSE | PFIZER INC. (US) | 1982-09-28 | — | — | US | disclosed |
| US-4282242-A | HYPOGLYCEMIC AGENTS | PFIZER INC. (US) | 1981-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220362375-A1 | METHODS OF RATIONAL NICOTINE HAPTEN DESIGN AND USES THEREOF | NAPRT, CHRNG, CHRNB2 | CYP3A4 251/4885SNCA 1879/4885ALDH1A1 655/4885 |
| US-11712467-B2 | Methods of rational nicotine hapten design and uses thereof | NAPRT, CHRNG, CHRNB2 | CYP3A4 251/4885SNCA 1879/4885ALDH1A1 655/4885 |
| US-11357848-B2 | Methods of rational nicotine hapten design and uses thereof | NAPRT, CHRNG, CHRNB2 | CYP3A4 251/4885SNCA 1879/4885ALDH1A1 655/4885 |
| US-20180125969-A1 | METHODS OF RATIONAL NICOTINE HAPTEN DESIGN AND USES THEREOF | NAPRT, CHRNG, CHRNB2 | CYP3A4 251/4885SNCA 1879/4885ALDH1A1 655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.