Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 4/20 | 0.53 |
| ▸ | CA1 | P00915 | 4/20 | 0.53 |
| ▸ | CA2 | P00918 | 4/20 | 0.53 |
| ▸ | CA7 | P43166 | 4/20 | 0.53 |
| ▸ | CA9 | Q16790 | 4/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.53 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL27813064 | 0.98 | CA12 (0.52) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9495909 | 0.85 | LMNA (0.58) | ESR1LMNACYP1A2CYP3A4TSHR | |
| 1,2,4-Triazole SCHEMBL25272216 | 0.85 | CA12 (0.41) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9496726 | 0.82 | ESR1 (0.58) | ESR1LMNACYP1A2CYP3A4TSHR | |
| SCHEMBL20157277 | 0.81 | MAPT (0.44) | CA12CA1CA2CA7CA9 | |
| SCHEMBL9212901 | 0.81 | SIRT2 (0.40) | CA12CA1CA2CA7CA9 | |
| SCHEMBL29210121 | 0.81 | ACACB (0.38) | CA12CA1CA2CA7CA9 | |
| SCHEMBL4524002 | 0.80 | ALDH1A1 (0.59) | ESR1LMNACYP1A2CYP3A4TSHR | |
| SCHEMBL5162771 | 0.79 | ALDH1A1 (0.49) | LMNATSHRHPGDSMN1; SMN2RAB9A | |
| SCHEMBL29132915 | 0.79 | LMNA (0.42) | ESR1LMNACYP1A2CYP3A4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 182 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2041085-A1 | PYRROLE DERIVATIVES AND THEIR METHODS OF USE | Abbott Laboratories (US) | 2009-04-01 | — | — | EP | claimed |
| WO-2008002974-A1 | PYRROLE DERIVATIVES AND THEIR METHODS OF USE | ABBOTT LABORATORIES (US) | 2008-01-03 | — | — | WO | claimed |
| EP-1244620-A1 | CYCLIC AMP-SPECIFIC PHOSPHODIESTERASE INHIBITORS | ICOS CORPORATION (US) | 2002-10-02 | — | — | EP | claimed |
| WO-2001047880-A1 | CYCLIC AMP-SPECIFIC PHOSPHODIESTERASE INHIBITORS | ICOS CORPORATION (US) | 2001-07-05 | — | — | WO | claimed |
| CN-114149411-B | Vonoprazan intermediate and preparation method and application thereof | 鲁南制药集团股份有限公司 | 2025-05-16 | — | — | CN | disclosed |
| CN-119233974-A | Indolone derivative and application thereof | 康百达（四川）生物医药科技有限公司 | 2024-12-31 | — | — | CN | disclosed |
| CN-118974016-A | Indolone derivative and application thereof in medicine | 康百达（四川）生物医药科技有限公司 | 2024-11-15 | — | — | CN | disclosed |
| CN-114174294-B | Novel compounds for inhibiting JANUS kinase 1 | 人类制药有限公司 | 2024-10-25 | — | — | CN | disclosed |
| CN-115745971-B | PARP7 inhibitor and application thereof | 北京华森英诺生物科技有限公司 | 2024-07-30 | — | — | CN | disclosed |
| US-20240245699-A1 | PYRROLE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SERVIER LAB (FR) | 2024-07-25 | — | — | US | disclosed |
| CN-114644750-B | Phosphate-based polymer, preparation method thereof and hybrid nano reinforcing agent prepared from phosphate-based polymer for concrete | 博特新材料泰州有限公司 | 2024-05-14 | — | — | CN | disclosed |
| CN-117659006-A | Nitrogen-containing heteroaryl compound, preparation method thereof and application thereof in medicine | 江苏恒瑞医药股份有限公司 | 2024-03-08 | — | — | CN | disclosed |
| EP-0708090-A1 | Intermediates useful for the synthesis of pesticides | RHONE-POULENC AGROCHIMIE (FR) | 1996-04-24 | — | — | EP | disclosed |
| US-RE35096-E | Antilipemic, anticholesterol, arteriosclerosis | MITSUBISHI CHEMICAL CORPORATION (JP) | 1995-11-21 | — | — | US | disclosed |
| EP-0267794-B1 | PROCESS FOR PREPARING POLYOLEFINS | Nippon Petrochemicals Co., Ltd. (JP) | 1993-05-05 | — | — | EP | disclosed |
| US-5082856-A | Hyperlipemia, arteriosclerosis | MITSUBISHI KASEI CORPORATION (JP) | 1992-01-21 | — | — | US | disclosed |
| EP-0347902-A2 | Pyrrolecarboxylic acid derivatives | Mitsubishi Chemical Corporation (JP) | 1989-12-27 | — | — | EP | disclosed |
| EP-0267794-A2 | Process for preparing polyolefins | Nippon Petrochemicals Co., Ltd. (JP) | 1988-05-18 | — | — | EP | disclosed |
| US-4525555-A | TITANIUM COMPOUND SUPPORTED ON SOLID REACTION PRODUCT OF MAGNESIUM HALIDE, SILOXANES, ORGANIC COMPOUNDS | NIPPON OIL COMPANY, LIMITED (JP) | 1985-06-25 | — | — | US | disclosed |
| US-4369277-A | Pyrrole-stabilized chlorine-containing thermoplastics | CIBA-GEIGY CORPORATION (US) | 1983-01-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240245699-A1 | PYRROLE COMPOUNDS, A PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | PDCD11, RRM2B, RRM2 | CA12 3985/4885CA1 3490/4885CA2 4164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.