Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 11/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | KDM1A | O60341 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | METAP2 | P50579 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.44 |
| ▸ | CKS1B | P61024 | 1/20 | 0.44 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7850997 | 0.86 | PDE10A (0.65) | PDE10AALDH1A1 | |
| SCHEMBL7840858 | 0.84 | PDE10A (0.54) | PDE10AALDH1A1KDM1ANPC1RAB9A | |
| SCHEMBL7840628 | 0.82 | ALDH1A1 (0.67) | PDE10AALDH1A1KDM1ANPC1RAB9A | |
| SCHEMBL11031977 | 0.79 | NPC1 (0.47) | PDE10AALDH1A1KDM1ANPC1RAB9A | |
| SCHEMBL9830879 | 0.76 | ALDH1A1 (0.55) | ALDH1A1KDM1ANPC1RAB9AABCB1 | |
| SCHEMBL7849624 | 0.76 | PDE10A (0.64) | PDE10AALDH1A1KDM1ANPC1RAB9A | |
| SCHEMBL10685876 | 0.75 | ALDH1A1 (0.51) | PDE10AALDH1A1KDM1ANPC1RAB9A | |
| SCHEMBL9534926 | 0.74 | ALDH1A1 (0.63) | PDE10AALDH1A1KDM1ANPC1RAB9A | |
| SCHEMBL9831482 | 0.74 | LMNA (0.59) | PDE10AALDH1A1KDM1ANPC1RAB9A | |
| SCHEMBL9534282 | 0.73 | ALDH1A1 (0.56) | PDE10AALDH1A1KDM1ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0717743-B1 | N-ARYL 1,2,4]TRIAZOLO 1,5-a]PYRIDINE-2-SULFONAMIDE HERBICIDES | DOW AGROSCIENCES LLC (US) | 2001-11-14 | — | — | EP | disclosed |
| EP-0972774-A2 | 2-Benzylthio-8-amino(1,2,4)triazolo(1,5-pyridines | Dow AgroSciences LLC (US) | 2000-01-19 | — | — | EP | disclosed |
| EP-0789698-B1 | N-(1-ETHYL-4-PYRAZOLYL)TRIAZOLOAZINESULFONAMIDE HERBICIDES | DOW AGROSCIENCES LLC (US) | 1999-07-07 | — | — | EP | disclosed |
| EP-0789698-A1 | N-(1-ETHYL-4-PYRAZOLYL)TRIAZOLOAZINESULFONAMIDE HERBICIDES | DOWELANCO (US) | 1997-08-20 | — | — | EP | disclosed |
| WO-1997008172-A1 | N-(1-ETHYL-4-PYRAZOLYL)TRIAZOLOAZINESULFONAMIDE HERBICIDES | DOWELANCO (US) | 1997-03-06 | — | — | WO | disclosed |
| US-5571775-A | EFFECTIVE ON A BROAD SPECTRUM OF VEGETATION AT LOW APPLICATION RATES | DOWELANCO (US) | 1996-11-05 | — | — | US | disclosed |
| EP-0717743-A1 | N-ARYL 1,2,4]TRIAZOLO 1,5-a]PYRIDINE-2-SULFONAMIDE HERBICIDES | DOWELANCO (US) | 1996-06-26 | — | — | EP | disclosed |
| WO-1996001826-A1 | N-ARYL[1,2,4]TRIAZOLO[1,5-a]PYRIDINE-2-SULFONAMIDE HERBICIDES | DOWELANCO (US) | 1996-01-25 | — | — | WO | disclosed |