Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 13/20 | 0.47 |
| ▸ | PADI4 | Q9UM07 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7854807 | 0.90 | TACR1 (0.48) | TACR1PADI4KDM4ELMNAKMT2A | |
| SCHEMBL7850939 | 0.89 | TACR1 (0.52) | TACR1KDM4E | |
| SCHEMBL7851720 | 0.84 | TACR1 (0.46) | TACR1KDM4EFEN1TDP1 | |
| SCHEMBL7841672 | 0.80 | TACR1 (0.52) | TACR1 | |
| SCHEMBL7850548 | 0.80 | TACR1 (0.63) | TACR1KDM4ESMN1; SMN2FEN1 | |
| SCHEMBL7851995 | 0.79 | TACR1 (0.62) | TACR1KDM4E | |
| SCHEMBL7850487 | 0.79 | TACR1 (0.59) | TACR1PADI4KDM4ELMNAKMT2A | |
| SCHEMBL7852343 | 0.77 | TACR1 (0.53) | TACR1KDM4EKMT2A | |
| SCHEMBL7851596 | 0.77 | TACR1 (0.52) | TACR1KDM4EKMT2A | |
| SCHEMBL7851698 | 0.77 | TACR1 (0.47) | TACR1FEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0652218-B1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-07-11 | — | — | EP | disclosed |
| US-5585385-A | USEFUL IN TREATING DISORDERS OF MICTURITION; ADMINISTERING TO INHIBIT PLASMA EXTRAVASATION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-17 | — | — | US | disclosed |
| EP-0652218-A1 | Heterocyclic compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1995-05-10 | — | — | EP | disclosed |