Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 14/20 | 0.62 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.44 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7850939 | 0.91 | TACR1 (0.52) | TACR1MAPK14RPS6KB1KDM4E | |
| SCHEMBL7849465 | 0.89 | TACR1 (0.63) | TACR1MAPK14AHR | |
| SCHEMBL7850548 | 0.89 | TACR1 (0.63) | TACR1KDM4E | |
| SCHEMBL7852343 | 0.86 | TACR1 (0.53) | TACR1KDM4E | |
| SCHEMBL7851596 | 0.81 | TACR1 (0.52) | TACR1KDM4E | |
| SCHEMBL7849923 | 0.80 | TACR1 (0.59) | TACR1 | |
| SCHEMBL7841672 | 0.80 | TACR1 (0.52) | TACR1MAPK14 | |
| SCHEMBL7851972 | 0.79 | TACR1 (0.81) | TACR1 | |
| SCHEMBL7852053 | 0.79 | TACR1 (0.47) | TACR1KDM4E | |
| SCHEMBL7850487 | 0.79 | TACR1 (0.59) | TACR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0652218-B1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-07-11 | — | — | EP | disclosed |
| US-5585385-A | USEFUL IN TREATING DISORDERS OF MICTURITION; ADMINISTERING TO INHIBIT PLASMA EXTRAVASATION | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-12-17 | — | — | US | disclosed |
| EP-0652218-A1 | Heterocyclic compounds, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1995-05-10 | — | — | EP | disclosed |