Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.53 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.53 |
| ▸ | IDO1 | P14902 | 2/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.48 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
| ▸ | SPHK2 | Q9NRA0 | 1/20 | 0.42 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.42 |
| ▸ | F9 | P00740 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6987612 | 0.83 | MAOB (0.58) | BCHEL3MBTL1ALDH1A1GAA | |
| SCHEMBL4779293 | 0.78 | ABCB1 (0.62) | PARP10PARP14IDO1ABCB1BCHE | |
| SCHEMBL15033480 | 0.77 | NPC1 (0.57) | PARP10PARP14IDO1ABCB1BCHE | |
| SCHEMBL29036345 | 0.77 | IDO1 (0.55) | PARP10PARP14IDO1ABCB1BCHE | |
| SCHEMBL10983336 | 0.76 | NQO1 (0.48) | MEN1KMT2AALDH1A1GAAHTT | |
| SCHEMBL13439791 | 0.76 | IDO1 (0.50) | PARP10PARP14IDO1ABCB1BCHE | |
| SCHEMBL13439832 | 0.76 | ABCB1 (0.52) | PARP10PARP14IDO1ABCB1PARP15 | |
| SCHEMBL28624844 | 0.76 | ALDH1A1 (0.53) | PARP10PARP14IDO1ABCB1BCHE | |
| SCHEMBL15033567 | 0.76 | IDO1 (0.58) | PARP10PARP14IDO1ABCB1BCHE | |
| SCHEMBL31172139 | 0.75 | MAOB (0.57) | PARP10PARP14IDO1ABCB1PARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0640606-B1 | Thienopyrimidine derivatives, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2001-11-07 | — | — | EP | disclosed |