SCHEMBL785255

SCHEMBL785255

Cc1ccc(-c2ccc(-c3ccc(-c4cccs4)cc3)s2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.53
KDM4E B2RXH2 4/20 0.53
NPC1 O15118 2/20 0.53
NFKB1 P19838 2/20 0.53
RAB9A P51151 2/20 0.53
NFKB2 Q00653 2/20 0.53
RELA Q04206 2/20 0.53
SMN1; SMN2 Q16637 2/20 0.53
L3MBTL1 Q9Y468 3/20 0.50
LMNA P02545 2/20 0.50
LTA4H P09960 1/20 0.50
TP53 P04637 1/20 0.50
MAPK1 P28482 1/20 0.50
MAPT P10636 3/20 0.47
LPL P06858 1/20 0.45
LIPG Q9Y5X9 1/20 0.45
CYP17A1 P05093 1/20 0.44
CYP11B1 P15538 1/20 0.44
CYP11B2 P19099 1/20 0.44
KCNH2 Q12809 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10035775 0.94 ALDH1A1 (0.51) ALDH1A1KDM4ENPC1NFKB1RAB9A
SCHEMBL152530 0.92 ALDH1A1 (0.59) ALDH1A1KDM4ENPC1NFKB1RAB9A
SCHEMBL20662905 0.90 ALDH1A1 (0.58) ALDH1A1KDM4ENPC1NFKB1RAB9A
SCHEMBL15274500 0.90 ALDH1A1 (0.58) ALDH1A1KDM4ENPC1NFKB1RAB9A
SCHEMBL28360518 0.90 ALDH1A1 (0.58) ALDH1A1KDM4ENPC1NFKB1RAB9A
SCHEMBL12408419 0.89 LTA4H (0.59) ALDH1A1KDM4EL3MBTL1LTA4HMAPT
SCHEMBL29363583 0.89 LTA4H (0.59) ALDH1A1KDM4EL3MBTL1LTA4HMAPT
SCHEMBL14190036 0.89 LTA4H (0.59) ALDH1A1KDM4EL3MBTL1LTA4HMAPT
SCHEMBL24141652 0.86 LTA4H (0.48) ALDH1A1KDM4ENPC1NFKB1RAB9A
SCHEMBL14565390 0.85 APP (0.46) ALDH1A1KDM4ENPC1NFKB1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120068123-A1 USE OF PHTHALOCYANINE COMPOUNDS WITH ARYL OR HETARYL SUBSTITUENTS IN ORGANIC SOLAR CELLS BASF SE (DE) 2012-03-22 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120068123-A1 USE OF PHTHALOCYANINE COMPOUNDS WITH ARYL OR HETARYL SUBSTITUENTS IN ORGANIC SOLAR CELLS RB1, NRAS, HLA-B ALDH1A1 761/4885KDM4E 2337/4885NPC1 1583/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.