SCHEMBL785259

SCHEMBL785259

Cc1cc(O)c(C(C)(C)C)c(C)c1N

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 3/20 0.45
ALDH1A1 P00352 9/20 0.42
MAPT P10636 5/20 0.42
GAA P10253 3/20 0.42
ALOX15 P16050 5/20 0.37
TSHR P16473 3/20 0.37
CYP3A4 P08684 3/20 0.37
TP53 P04637 3/20 0.37
TDP1 Q9NUW8 3/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
MAPK1 P28482 2/20 0.37
HIF1A Q16665 2/20 0.37
PKM P14618 2/20 0.35
MEN1 O00255 1/20 0.35
RECQL P46063 1/20 0.35
KMT2A Q03164 1/20 0.35
KDM4E B2RXH2 4/20 0.34
CYP1A2 P05177 3/20 0.34
ATP2A2 P16615 1/20 0.34
ATP2A3 Q93084 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8657395 0.80 ALDH1A1 (0.41) POLBALDH1A1MAPTGAAALOX15
SCHEMBL395986 0.80 ALDH1A1 (0.41) POLBALDH1A1MAPTGAAALOX15
SCHEMBL784959 0.78 CYP2C9 (0.43) POLBALDH1A1MAPTALOX15TSHR
SCHEMBL15504705 0.77 ALDH1A1 (0.41) POLBALDH1A1MAPTGAAALOX15
SCHEMBL2741242 0.75 ALDH1A1 (0.50) POLBALDH1A1MAPTGAAALOX15
SCHEMBL17914229 0.75 ALDH1A1 (0.61) POLBALDH1A1MAPTGAAALOX15
Hydrochloric Acid SCHEMBL5901427 0.73 ALDH1A1 (0.54) POLBALDH1A1MAPTGAAALOX15
SCHEMBL12149768 0.73 ACHE (0.42) POLBALDH1A1MAPTGAAALOX15
SCHEMBL7941748 0.72 POLB (0.56) POLBALDH1A1TSHRCYP3A4TP53
SCHEMBL784926 0.72 ALDH1A1 (0.35) ALDH1A1MAPTGAAALOX15TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8691933-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2014-04-08 US disclosed
US-20140011901-A1 Stabilized Polyolefin Compositions POLNOX CORPORATION (US) 2014-01-09 US disclosed
US-20140011901-A1 Stabilized Polyolefin Compositions POLNOX CORPORATION (US) 2014-01-09 US disclosed
US-8481670-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2013-07-09 US disclosed
US-20130072586-A1 Stabilized Polyolefin Compositions POLNOX CORPORATION (US) 2013-03-21 US disclosed
US-8252884-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2012-08-28 US disclosed
US-20120071596-A1 STABILIZED POLYOLEFIN COMPOSITIONS POLNOX CORPORATION 2012-03-22 US disclosed
US-8008423-B2 Stabilized polyolefin compositions POLNOX CORPORATION (US) 2011-08-30 US disclosed
US-20100305251-A1 STABILIZED POLYOLEFIN COMPOSITIONS POLNOX CORPORATION 2010-12-02 US disclosed