Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 2/20 | 0.58 |
| ▸ | CTSK | P43235 | 7/20 | 0.57 |
| ▸ | CTSL | P07711 | 6/20 | 0.57 |
| ▸ | HTRA1 | Q92743 | 1/20 | 0.55 |
| ▸ | CTSB | P07858 | 3/20 | 0.55 |
| ▸ | CTSS | P25774 | 2/20 | 0.55 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.54 |
| ▸ | REN | P00797 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7846232 | 0.89 | CAPN1 (0.64) | CAPN1CTSKCTSLHTRA1CTSB | |
| SCHEMBL10975356 | 0.83 | CAPN1 (0.73) | CAPN1CTSKCTSLHTRA1CTSB | |
| SCHEMBL12242779 | 0.82 | CTSK (0.75) | CAPN1CTSKCTSLCTSBCTSS | |
| SCHEMBL22415806 | 0.82 | CTSK (0.75) | CAPN1CTSKCTSLCTSBCTSS | |
| SCHEMBL14415432 | 0.82 | CTSK (0.75) | CAPN1CTSKCTSLCTSBCTSS | |
| SCHEMBL7846358 | 0.81 | CAPN1 (0.67) | CAPN1CTSKCTSLHTRA1CTSB | |
| SCHEMBL31705215 | 0.80 | CAPN1 (0.74) | CAPN1CTSKCTSLHTRA1CTSB | |
| SCHEMBL8014485 | 0.80 | CAPN1 (0.72) | CAPN1CTSKCTSLHTRA1CTSB | |
| SCHEMBL21219280 | 0.80 | CAPN1 (0.74) | CAPN1CTSKCTSLHTRA1CTSB | |
| SCHEMBL21219352 | 0.80 | CAPN1 (0.74) | CAPN1CTSKCTSLHTRA1CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6534530-B1 | Administering (benzo)thiazole peptidomimetic as viricide; protease inhibitors | AGOURON PHARMACEUTICALS, INC. | 2003-03-18 | — | — | US | disclosed |
| US-6534530-B1 | Administering (benzo)thiazole peptidomimetic as viricide; protease inhibitors | AGOURON PHARMACEUTICALS, INC. | 2003-03-18 | — | — | US | disclosed |