Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.30 |
| ▸ | MAOB | P27338 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7853483 | 0.98 | BACE1 (0.33) | HRH4BACE1 | |
| SCHEMBL7853195 | 0.98 | BACE1 (0.33) | HRH4BACE1 | |
| SCHEMBL2766032 | 0.98 | BACE1 (0.33) | HRH4BACE1 | |
| SCHEMBL7854037 | 0.95 | — | — | |
| SCHEMBL7855844 | 0.62 | MAOA (0.30) | MAOAMAOB | |
| SCHEMBL7852052 | 0.60 | CYP11B2 (0.31) | — | |
| SCHEMBL7845102 | 0.60 | CYP11B2 (0.31) | — | |
| SCHEMBL7855962 | 0.60 | CYP11B2 (0.31) | — | |
| SCHEMBL7856375 | 0.57 | — | — | |
| SCHEMBL7854923 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719258-B1 | CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS | OTSUKA PHARMA CO LTD (JP) | 2001-10-31 | — | — | EP | disclosed |
| US-5786367-A | OXYGEN SCAVENGERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-07-28 | — | — | US | disclosed |