Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | LIG1 | P18858 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SETDB1 | Q15047 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28979266 | 0.75 | AOC3 (0.51) | MAPK1 | |
| SCHEMBL97167 | 0.72 | KMT2A (0.47) | KMT2AMEN1MAPK1HPGDALDH1A1 | |
| SCHEMBL7856800 | 0.70 | KMT2A (0.40) | KMT2AMEN1HPGDCYP3A4KDM4E | |
| SCHEMBL30462587 | 0.70 | ADRA2A (0.50) | ADRA2AADRA2BADRA2CMAPK1HPGD | |
| SCHEMBL3994512 | 0.70 | ADRA2A (0.50) | ADRA2AADRA2BADRA2CMAPK1HPGD | |
| SCHEMBL11112128 | 0.69 | ADRA2A (0.43) | ADRA2AADRA2BADRA2CKMT2AMEN1 | |
| SCHEMBL9321659 | 0.68 | MGLL (0.56) | ADRA2AADRA2BADRA2CMAPK1HPGD | |
| SCHEMBL10569169 | 0.68 | SMN1; SMN2 (0.40) | ADRA2AADRA2BADRA2CKMT2AMEN1 | |
| SCHEMBL11434198 | 0.67 | MEN1 (0.44) | KMT2AMEN1MAPK1HPGDPOLB | |
| SCHEMBL11437152 | 0.66 | SMN1; SMN2 (0.45) | ADRA2AADRA2BADRA2CKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1084330-C | Cydic amide derivatives | OTSUKA PHARMA CO LTD (JP) | 2002-05-08 | — | — | CN | disclosed |
| EP-0719258-B1 | CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS | OTSUKA PHARMA CO LTD (JP) | 2001-10-31 | — | — | EP | disclosed |
| US-5786367-A | OXYGEN SCAVENGERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-07-28 | — | — | US | disclosed |
| CN-1130377-A | Cyclic amide derivatives | OTSUKA PHARMA CO LTD (JP) | 1996-09-04 | — | — | CN | disclosed |