Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 7/20 | 0.45 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7854015 | 0.95 | PTPN1 (0.45) | PTPN1HSD17B1HTTHPGDMEN1 | |
| SCHEMBL7854024 | 0.83 | PTPN1 (0.38) | PTPN1MAPTATAD2CHRM1 | |
| SCHEMBL7853603 | 0.81 | PTPN1 (0.38) | PTPN1MAPTATAD2CHRM1 | |
| SCHEMBL7848198 | 0.79 | PTPN1 (0.38) | PTPN1MEN1KMT2A | |
| SCHEMBL7853422 | 0.79 | ALDH1A1 (0.39) | PTPN1HSD17B1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL7853425 | 0.79 | ALDH1A1 (0.39) | PTPN1HSD17B1HTTKMT2ASMN1; SMN2 | |
| SCHEMBL7852912 | 0.77 | PTPN1 (0.40) | PTPN1MEN1KMT2A | |
| SCHEMBL7856163 | 0.74 | SRD5A1 (0.38) | PTPN1SRD5A1 | |
| SCHEMBL7852247 | 0.74 | SRD5A1 (0.38) | PTPN1SRD5A1 | |
| SCHEMBL10746984 | 0.74 | HSD17B1 (0.39) | PTPN1HSD17B1HTTHPGDSRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719258-B1 | CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS | OTSUKA PHARMA CO LTD (JP) | 2001-10-31 | — | — | EP | disclosed |
| US-5786367-A | OXYGEN SCAVENGERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-07-28 | — | — | US | disclosed |