Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | XBP1 | P17861 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CES2 | O00748 | 4/20 | 0.38 |
| ▸ | CES1 | P23141 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | DAO | P14920 | 1/20 | 0.38 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAOA | P21397 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18380950 | 0.80 | AKT1 (0.38) | AKT1MEN1KMT2AMAPTLMNA | |
| SCHEMBL1071814 | 0.80 | AKT1 (0.38) | AKT1MEN1KMT2AMAPTLMNA | |
| SCHEMBL1071816 | 0.80 | AKT1 (0.38) | AKT1MEN1KMT2AMAPTLMNA | |
| Acetaldehyde SCHEMBL10909685 | 0.77 | AKT1 (0.50) | AKT1MEN1KMT2AMAPTLMNA | |
| SCHEMBL108144 | 0.76 | AKT1 (0.54) | AKT1MEN1KMT2AMAPTLMNA | |
| SCHEMBL24254437 | 0.75 | MEN1 (0.42) | AKT1MEN1KMT2AMAPTLMNA | |
| SCHEMBL6258204 | 0.75 | MEN1 (0.42) | AKT1MEN1KMT2AMAPTLMNA | |
| SCHEMBL18381166 | 0.75 | MEN1 (0.38) | AKT1MEN1KMT2AMAPTLMNA | |
| Bicarbonate SCHEMBL11378162 | 0.75 | AKT1 (0.43) | AKT1MEN1KMT2AMAPTLMNA | |
| SCHEMBL12919933 | 0.74 | AKT1 (0.41) | AKT1MEN1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1084330-C | Cydic amide derivatives | OTSUKA PHARMA CO LTD (JP) | 2002-05-08 | — | — | CN | disclosed |
| EP-0719258-B1 | CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS | OTSUKA PHARMA CO LTD (JP) | 2001-10-31 | — | — | EP | disclosed |
| EP-0582926-B1 | Piperazin-2,3-diones as plant growth regulators | BASF AG (DE) | 1998-12-23 | — | — | EP | disclosed |
| US-5786367-A | OXYGEN SCAVENGERS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1998-07-28 | — | — | US | disclosed |
| CN-1130377-A | Cyclic amide derivatives | OTSUKA PHARMA CO LTD (JP) | 1996-09-04 | — | — | CN | disclosed |
| EP-0719258-A1 | CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-07-03 | — | — | EP | disclosed |
| WO-1996002508-A1 | CYCLIC AMIDE DERIVATIVES FOR PROTECTING AGAINST ULTRAVIOLET RAYS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1996-02-01 | — | — | WO | disclosed |
| US-5326743-A | Piperazine-2,3-diones as plant growth regulators | BASF AKTIENGESELLSCHAFT (DE) | 1994-07-05 | — | — | US | disclosed |
| EP-0469423-B1 | Oxalyl-bishydroxamic acid derivatives, their preparation and plant growth regulating agents containing them | BASF AG (DE) | 1994-06-15 | — | — | EP | disclosed |
| EP-0582926-A1 | Piperazin-2,3-diones as plant growth regulators | BASF Aktiengesellschaft (DE) | 1994-02-16 | — | — | EP | disclosed |
| EP-0464408-B1 | Process for preparing star compounds | SEKISUI CHEMICAL CO LTD (JP) | 1994-01-12 | — | — | EP | disclosed |
| US-5102966-A | Addition polymerization of unsaturated ethers using an unsaturated alkenyl polyether adduct as initiator and a cation-donating compound | SEKISUI CHEMICAL CO., LTD. (JP) | 1992-04-07 | — | — | US | disclosed |
| EP-0469423-A1 | Oxalyl-bishydroxamic acid derivatives, their preparation and plant growth regulating agents containing them | BASF Aktiengesellschaft (DE) | 1992-02-05 | — | — | EP | disclosed |
| EP-0464408-A1 | Process for preparing star compounds | SEKISUI CHEMICAL CO., LTD. (JP) | 1992-01-08 | — | — | EP | disclosed |
| US-5017724-A | Antihypoxic, CNS | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-21 | — | — | US | disclosed |
| EP-0267024-B1 | HYDROFLUORENE DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |
| EP-0267024-A2 | Hydrofluorene derivatives | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-05-11 | — | — | EP | disclosed |