Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | PHGDH | O43175 | 4/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7618049 | 0.84 | ALDH1A1 (0.41) | HPGDMAPTKMT2ARAB9AALDH1A1 | |
| SCHEMBL7619039 | 0.83 | GRM5 (0.36) | HPGDMAPTKMT2ARAB9AALDH1A1 | |
| SCHEMBL7697320 | 0.82 | ERN1 (0.36) | PKMPHGDHHPGDTSHRSMN1; SMN2 | |
| SCHEMBL6918700 | 0.78 | AKR1C3 (0.40) | PKMPHGDHAKR1C3TSHRMAPT | |
| SCHEMBL23388477 | 0.76 | PKM (0.46) | PKMPHGDHHPGDAKR1C3KDM4E | |
| SCHEMBL5176948 | 0.73 | PHGDH (0.57) | PHGDHHPGDAKR1C3TSHRKMT2A | |
| SCHEMBL29119937 | 0.72 | PHGDH (0.58) | PKMPHGDHHPGDAKR1C3MAPT | |
| SCHEMBL3778711 | 0.69 | HPGD (0.58) | HPGDTSHRKDM4EKMT2AALDH1A1 | |
| SCHEMBL6920038 | 0.69 | AKR1C3 (0.40) | PKMPHGDHHPGDAKR1C3TSHR | |
| SCHEMBL5794408 | 0.68 | SMN1; SMN2 (0.60) | TSHRKDM4EKMT2ASMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1140814-A2 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000039081-A2 | CELL ADHESION-INHIBITING ANTIINFLAMMATORY AND IMMUNE-SUPPRESSIVE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-07-06 | — | — | WO | disclosed |