Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 4/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.63 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | RECQL | P46063 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 3/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7854551 | 0.80 | MAPT (0.56) | ALDH1A1MAPTPOLBL3MBTL1MEN1 | |
| SCHEMBL7224446 | 0.79 | HPGD (0.46) | HPGDALDH1A1POLBSMN1; SMN2RAB9A | |
| SCHEMBL7846596 | 0.78 | HPGD (0.45) | HPGDALDH1A1POLBTSHRSMN1; SMN2 | |
| SCHEMBL7855101 | 0.78 | MAPK7 (0.59) | ALDH1A1HSD17B10POLBMAPK1 | |
| SCHEMBL7855604 | 0.77 | MAPK14 (0.60) | HPGDALDH1A1POLBRECQLTSHR | |
| SCHEMBL7854191 | 0.77 | ALDH1A1 (0.44) | HPGDALDH1A1ALOX15MAPTPOLB | |
| SCHEMBL7845245 | 0.77 | POLB (0.46) | HPGDALDH1A1ALOX15HSD17B10POLB | |
| SCHEMBL7846577 | 0.77 | SMN1; SMN2 (0.54) | HPGDALDH1A1POLBKDM4ETSHR | |
| SCHEMBL7854568 | 0.76 | POLB (0.78) | HPGDALDH1A1POLBL3MBTL1KDM4E | |
| SCHEMBL6358692 | 0.76 | HPGD (0.66) | HPGDALDH1A1HSD17B10MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1088481-A2 | Fungicides for the control of take-all disease of plants | MONSANTO COMPANY (US) | 2001-04-04 | — | — | EP | disclosed |